Life Sciences Commons^™

Cartilage On The Move: Cartilage Lineage Tracing During Tadpole Metamorphosis, Ryan R. Kerney, Alison L. Brittain, Brian K. Hall, Daniel R. Buchholz

Biology Faculty Publications

The reorganization of cranial cartilages during tadpole metamorphosis is a set of complex processes. The fates of larval cartilage-forming cells (chondrocytes) and sources of adult chondrocytes are largely unknown. Individual larval cranial cartilages may either degenerate or remodel, while many adult cartilages appear to form de novo during metamorphosis. Determining the extent to which adult chondrocytes/cartilages are derived from larval chondrocytes during metamorphosis requires new techniques in chondrocyte lineage tracing. We have developed two transgenic systems to label cartilage cells throughout the body with fluorescent proteins. One system strongly labels early tadpole cartilages only. The other system inducibly labels forming …

The Effect Of Medetomidine On The Burying Speed Of Corbicula Fluminea, Andrew K. Schmucker

Student Publications

A new anti-fouling drug, medetomidine, was tested to determine if it reduced the burying speed of a freshwater alien-invasive bivalve species, Corbicula fluminea. Corbicula are known to damage underwater structures and must be managed with chemical paints. The burying speeds of Corbicula were measured both before and after exposure to two different concentrations of medetomidine. The burying speed of Corbicula before exposure to a 1x10^-6 M medetomidine solution was not significantly different from the burying speed after exposure (t=.55, df=21, p=.588). The burying speed of Corbicula was significantly slower after exposure to a 1x10^-5 M medetomidine solution …

Farmers Markets And The Local Food System: The Case Of Gettysburg, Pennsylvania, Paul A. Di Salvo, Claire Quinn, Robin Arnold, Caroline Clark, Suzanne Englot, Andrew Mello, Julia P. Mitchell, Emily Ruhl, Rebecca Taormina, Cashin Conover, Valerie Leone, Michael Mattaini, William Patton, Elizabeth Rouillard, Nicholas Smith-Herman, Jordan Swenson, Kelly Webster, Brian Wooldredge, Randall K. Wilson

Student Publications

In order to examine and obtain a better understanding of the local food system within Adams County, Pennsylvania, this study explores the characteristics and perspectives of the customers and vendors at the farmers markets in Gettysburg, Pennsylvania. Survey findings from the Gettysburg Farmers Market and the three Adams County Farmers Markets include customer demographic information, perspectives and shopping behavior as well as vendor product information, farm size and location and preference for market management. Introductory background information on the Farm Bill and the influence of agricultural practices on the environment, human health and nutrition and the relationship between farmers markets …

Pathogen Response Genes Mediate Caenorhabditis Elegans Innate Immunity, Hannah L. Anthony

Celebration

Innate immunity is crucial in the response and defense against pathogens for invertebrates and vertebrates alike. The soil nematode Caenorhabditis elegans is a useful model to study the eukaryotic innate immune response to microbial pathogenesis. Prior research indicates that the protein receptor FSHR-1 plays an important role in the innate recognition of intestinal infection due to pathogen consumption. Determining what genes are controlled by FSHR-1 may uncover an unknown pathway that could increase not only the comprehension of the C. elegans immune system but also innate immunity generally. To characterize the function of FSHR-1, four candidate pathogen response genes that …

Toxic Effects Of Copper, Cadmium, And Methoxychlor Shown By Neutral Red Retention Assay In Two Species Of Freshwater Molluscs, Nikolett Molnar, Peter Fong

Biology Faculty Publications

We used neutral red retention assay in lysosomes of digestive gland cells as an indicator for stress effects by the environmental contaminants Cu, Cd, and the pesticide methoxychlor in two freshwater molluscs, the unionid mussel, Elliptio complanata (Lightfoot) and the ramshorn snail Helisoma trivolvis (Say). Mussels and snails were exposed for 7 and 14 days to Cu and Cd each at nominal concentrations of 2.5 μg/L, 5.0 μg/L, and 10.0 μg/L, and to methoxychlor concentrations of 1.0 μg/L, 10.0μg/L, and 100.0 μg/L. Both mussels and snails exposed to Cu showed a significant increase in the percent of destabilized lysosomes compared …

Hyponatremia In The 2009 161-Km Western States Endurance Run, Martin D. Hoffman, Kristin J. Stuempfle, Ian R. Rogers, Louise B. Weschler, Tamara Hew-Butler

Health Sciences Faculty Publications

Purpose:To determine the incidence of exercise-associated hyponatremia (EAH), the associated biochemical measurements and risk factors for EAH, and whether there is an association between postrace blood sodium concentration ([Na⁺]) and changes in body mass among participants in the 2009 Western States Endurance Run, a 161-km mountain trail run.

Methods: Change in body mass, postrace [Na⁺], and blood creatine phosphokinase (CPK) concentration, and selected runner characteristics were evaluated among consenting competitors.

Results: Of the 47 study participants, 14 (30%) had EAH as defined by a postrace [Na⁺] /L. Postrace [Na^{+ …}

Conserving Our Cultural Heritage: The Role Of Fungi In Biodeterioration, Hanna Szczepanowska, A. R. Cavaliere

Biology Faculty Publications

The objects of cultural heritage are composed of varied materials which can be affected by diverse microbial communities. The study of these complex and heterogeneous assemblies of materials and microorganisms require an inter- and multi-disciplinary approach. Development of a strategy towards prevention, mitigation of biodeterioration and removal of microorganisms, especially fungi begins with the understanding of the materials' fabric, assessment of causes behind the biodeterioration, and the context in which it occurs.

Three aspects of biodeterioration of cultural heritage are discussed: 1) the multitude of bio-agents' on cultural heritage materials, 2) fungal interaction with substrates, and 3) prevention and conservation …