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Full-Text Articles in Life Sciences
Multi-Response Surface Optimisation Of Extrusion Cooking To Increase Soluble Dietary Fibre And Polyphenols In Lupin Seed Coat, Liezhou Zhong, Zhongxiang Fang, Mark L. Wahlqvist, Jonathan M. Hodgson, Stuart K. Johnson
Multi-Response Surface Optimisation Of Extrusion Cooking To Increase Soluble Dietary Fibre And Polyphenols In Lupin Seed Coat, Liezhou Zhong, Zhongxiang Fang, Mark L. Wahlqvist, Jonathan M. Hodgson, Stuart K. Johnson
Research outputs 2014 to 2021
The seed coat of the legume lupin which is rich in insoluble dietary fibre is a major by-product in human food applications. Extrusion cooking has been demonstrated to increase desirable soluble dietary fibre in the Australian sweet lupin seed coat. In this study, processing condition of twin-screw extrusion cooking was optimised using a central composite rotatable design to increase soluble dietary fibre in lupin seed coat from 44.17 g/kg up to 113.69 g/kg dry basis. The high levels of polyphenols in the seed coat were retained. The optimal extrusion conditions which achieved maximum levels of soluble dietary fibre, total free …
Pharmacokinetics And Antiangiogenic Studies Of Potassium Koetjapate In Rats, Seyedeh F. Jafari, Fouad Saleih R. Al-Suede, Ashwaq H.S. Yehya, Mohamed B.K. Ahamed, Armaghan Shafaei, Muhammad Asif, Yasser M. Tabana, Amin M.S.A. Majid, Hussein M. Baharetha
Pharmacokinetics And Antiangiogenic Studies Of Potassium Koetjapate In Rats, Seyedeh F. Jafari, Fouad Saleih R. Al-Suede, Ashwaq H.S. Yehya, Mohamed B.K. Ahamed, Armaghan Shafaei, Muhammad Asif, Yasser M. Tabana, Amin M.S.A. Majid, Hussein M. Baharetha
Research outputs 2014 to 2021
© 2020 Purpose: Koetjapic acid is an active compound of a traditional medicinal plant, Sandoricum koetjape. Although koetjapic acid has a promising anticancer potential, yet it is highly insoluble in aqueous solutions. To increase aqueous solubility of koetjapic acid, we have previously reported a chemical modification of koetjapic acid to potassium koetjapate (KKA). However, pharmacokinetics of KKA has not been studied. In this study, pharmacokinetics and antiangiogenic efficacy of KKA are investigated. Methods: Pharmacokinetics of KKA was studied after intravenous and oral administration in SD rats using HPLC. Anti-angiogenic efficacy of KKA was investigated in rat aorta, human endothelial cells …
Release Of Dissolved Organic Carbon From Seagrass Wrack And Its Implications For Trophic Connectivity, Paul S. Lavery, Kathryn M. Mcmahon, Julia Weyers, Mary C. Boyce, Carolyn Elizabeth Oldham
Release Of Dissolved Organic Carbon From Seagrass Wrack And Its Implications For Trophic Connectivity, Paul S. Lavery, Kathryn M. Mcmahon, Julia Weyers, Mary C. Boyce, Carolyn Elizabeth Oldham
Research outputs 2013
ABSTRACT: The export of old leaves and stems (wrack) from seagrass meadows provides a mechanism for trophic connectivity among coastal ecosystems. As little of this wrack is consumed by mesograzers, leached dissolved organic carbon (DOC) may determine the importance of wrack as a trophic subsidy. However, few studies have examined the effect of seagrass type or age on the release of DOC or its bioavailability. We examined the amount and composition of DOC released from different wrack: Posidonia sinuosa, Amphibolis antarctica and the alga Laurencia sp. We then examined the effect of age on DOC leaching from P. sinuosa wrack. …