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Axonal Regrowth Of Olfactory Sensory Neurons After Chemical Ablation And Removal Of Axonal Debris By Microglia, Rudy Chapman
Axonal Regrowth Of Olfactory Sensory Neurons After Chemical Ablation And Removal Of Axonal Debris By Microglia, Rudy Chapman
Electronic Theses and Dissertations
Olfactory sensory neurons (OSNs) are contained within the olfactory epithelium (OE) and are responsible for detecting odorant molecules in the air. The exposure of OSNs to the external environment is necessary for their function, but it also leaves them exposed to potentially harmful elements and thus results in a high turnover rate. Despite the high turnover, the olfactory sense is maintained throughout life through the division of a population of stem cells that produce new OSNs both during normal turnover and after an injury occurs in the OE. When new OSNs are born, they must extend axons from the OE …