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Full-Text Articles in Life Sciences

Analysis Of Synephrine Content In Bitter Orange (Citrus Aurantium L.) Dietary Supplements, Martha L. Newell Jul 2013

Analysis Of Synephrine Content In Bitter Orange (Citrus Aurantium L.) Dietary Supplements, Martha L. Newell

Theses and Dissertations

Many Americans are either currently taking, or have recently taken, non-prescription dietary supplements. These supplements claim to help prevent or relieve any number of ailments, but are not regulated by any governing body. One common use of dietary supplements is to aid in weight loss. Synephrine, the most abundant active component in bitter orange (Citrus aurantium L.) extracts, became a regular ingredient in weight loss supplements after the 2004 ephedra ban. The initial goal of this research was to use reverse phase high performance liquid chromatography (HPLC) to determine the synephrine content of five dietary supplements and compare …


Analysis Of Contributing Factors To Obesity In Children And Adolescents In Southwest Georgia, Sydney L. Worthy May 2013

Analysis Of Contributing Factors To Obesity In Children And Adolescents In Southwest Georgia, Sydney L. Worthy

Theses and Dissertations

Today more than 23 million U.S. children and adolescents are either obese or overweight. Hospital costs from obesity-related diseases in youth have increased from $35 million (0.43% of total hospital costs) during 1979 to 1981 to $127 million (1.79% of total costs) during 1997 to 1999. During the Pathway to Med School program, I collaborated with three other students to develop a research project on childhood and adolescent obesity. We conducted surveys at nine different primary care clinics in the southwest Georgia area. Approval was sought by the Institutional Review Board of Phoebe Putney Memorial Health System and Albany Area …


Characterization Of Bioreducible Poly(B-Amino Ester) Nanoparticles For Sirna Delivery, Bolivia Hurtado De Mendoza May 2013

Characterization Of Bioreducible Poly(B-Amino Ester) Nanoparticles For Sirna Delivery, Bolivia Hurtado De Mendoza

Theses and Dissertations

Glioblastoma multiforme (GBM) is one of the most malignant brain tumors affecting adults. It is characterized by necrotic tissue and abnormal vasculature, making it highly resistant to current cancer treatments. A promising alternative to standard cancer therapeutics is the use of drug delivery systems such as polymeric nanoparticles (NP) that deliver silencing RNA (siRNA) exclusively to tumor cells for gene knockdown. Presently, nonviral delivery vectors, such as poly(B-amino ester) (PBAE) NP, are beneficial delivery systems because they are less immunogenic and easier to chemically modify than vectors delivered by viruses. Although current formulations of PBAEs allow cargo release via hydrolytic …


Effects Of Short-Term Dewatering On Grazer Abundance And Algal Biomass In A Wastewater Treatment Algal Turf Scrubber, Emily Husted Jan 2013

Effects Of Short-Term Dewatering On Grazer Abundance And Algal Biomass In A Wastewater Treatment Algal Turf Scrubber, Emily Husted

Theses and Dissertations

Finding a new, clean, and sustainable energy source to replace fossil fuels is one of society’s most daunting challenges. Algae biomass is a promising renewable resource for biofuel production due to its efficient conversion of solar energy into chemical energy. Algal turf scrubbers (ATS™) systems mimic natural streams, flowing wastewater over hard substrates designed to encourage attached algae growth. This study focuses on the use of replicated ATS™ systems, because they are low maintenance, are effective for removing nutrient pollutants, model natural stream ecosystems, and can produce large volumes of harvestable algal feedstock for biofuel production. A challenge that occurs …