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Body Size Regulation Via Bmp Signaling In Caenorhabditis Elegans, Uday Madaan
Body Size Regulation Via Bmp Signaling In Caenorhabditis Elegans, Uday Madaan
Dissertations, Theses, and Capstone Projects
The body size of an organism can be a crucial determinant of access to nutrition, reproductive success and overall survival in the wild. However, how body size of an individual is determined is incompletely understood. Body size is a complex trait determined by multiple pathways and genes, making it difficult to understand the role of individual genes and pathways in determining overall size. In Caenorhabditis elegans, a homolog of Bone Morphogenetic Proteins (BMP) is a major regulator of body size; functional loss of DBL-1 leads to a small body size. Due to a drastic change in body size in dbl-1 …