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Pharmaceutical Sciences (PhD) Dissertations
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Viral Factors Influencing Early Infection Events During Ex-Vivo Kshv Infection, Ramina Nabiee
Viral Factors Influencing Early Infection Events During Ex-Vivo Kshv Infection, Ramina Nabiee
Pharmaceutical Sciences (PhD) Dissertations
The enigma of Kaposi Sarcoma Herpes Virus infection, and its persistence despite a quarter century of research on the virus, has given rise to an immediate need for addressing fundamental questions about basic immunology and virology knowledge regarding this virus. Kaposi Sarcoma Herpes Virus (KSHV), also known as Human Herpesvirus 8 (HHV8), is the etiological agent of Kaposi Sarcoma (KS) and other lymphoproliferative cancers, such as Multicentric Castleman’s Disease (MCD), Primary Effusion Lymphoma (PEL), and a newly discovered rare disease called KSHV Inflammatory Cytokines Syndrome (KICS). Epidemic KS, also known as AIDS-KS, is the most common cancer in untreated HIV …