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Effects Of Varying Doses Of Oral Bisphenol A Consumption On Type 2 Diabetes Risk Markers In Healthy Adults, Todd Hagobian, Alyssa Bird, Sean Stanelle, Dana Williams, Andrew Schaffner, Suzanne Phelan
Effects Of Varying Doses Of Oral Bisphenol A Consumption On Type 2 Diabetes Risk Markers In Healthy Adults, Todd Hagobian, Alyssa Bird, Sean Stanelle, Dana Williams, Andrew Schaffner, Suzanne Phelan
Kinesiology and Public Health
Objective
To determine the effects of varying doses of orally administered BPA on indices of glucose metabolism.
Methods
Eleven college students (21.0 ± 0.8 years; 24.2 ± 3.9 kg/m2) were randomized in a double-blinded, crossover fashion separated by >1 week to placebo (PL), deuterated BPA at 4 µg/kg body weight (BPA-4), and deuterated BPA at 50 µg/kg body weight (BPA-50). Total BPA, glucose, insulin, and C-peptide were assessed at baseline, minutes 15, 30, 45, 60, and every 30 minutes for 2 hours in response to a glucose tolerance test.
Results
There was a significant condition × time interaction …