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Congenic Strain Analysis Reveals Genes That Are Rapidly Evolving Components Of A Prezygotic Isolation Mechanism Mediating Incipient Reinforcement, Christina M. Laukaitis, Corina Mauss, Robert C. Karn
Congenic Strain Analysis Reveals Genes That Are Rapidly Evolving Components Of A Prezygotic Isolation Mechanism Mediating Incipient Reinforcement, Christina M. Laukaitis, Corina Mauss, Robert C. Karn
Scholarship and Professional Work - LAS
Two decades ago, we developed a congenic strain of Mus musculus, called b-congenic, by replacing the androgen-binding protein Abpa27a allele in the C3H/HeJ genome with the Abpa27b allele from DBA/2J. We and other researchers used this b-congenic strain and its C3H counterpart, the a-congenic strain, to test the hypothesis that, given the choice between signals from two strains with different a27 alleles on the same genetic background, test subjects would prefer the homosubspecific one. It was our purpose in undertaking this study to characterize the segment transferred from DBA to the C3H background in producing the b-congenic …