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Full-Text Articles in Life Sciences
Potential Regulation Of Breast Cancer Invasion By Thymidine Kinase 1, Eliza E. Bitter, Rachel M. Morris, Toni O. Mortimer, Kai Barlow, Abigail Schekall, Michelle H. Townsend, Jonathan Skidmore, Brett E. Pickett, Kim L. O'Neill
Potential Regulation Of Breast Cancer Invasion By Thymidine Kinase 1, Eliza E. Bitter, Rachel M. Morris, Toni O. Mortimer, Kai Barlow, Abigail Schekall, Michelle H. Townsend, Jonathan Skidmore, Brett E. Pickett, Kim L. O'Neill
Library/Life Sciences Undergraduate Poster Competition 2022
Breast cancer is the most common cancer in women and is largely treatable within the early stages of the disease. However, patient mortality drastically declines as the tumor begins to invade other tissues and metastasize, making aggressive phenotypes especially problematic to treat. Such treatment typically requires an aggressive and decisive multidisciplinary approach. The recent expansion of immunotherapy as a viable treatment option has greatly improved treatment outcomes, especially with aggressive breast cancer phenotypes. Thymidine kinase 1 (TK1) is a DNA salvage pathway enzyme that is highly expressed during S phase and involved in cell cycle repair. Past studies indicated that …