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Full-Text Articles in Life Sciences

The Effect Of Percussive Massage On Collagen Gene Expression In Skeletal Muscle, James Bartling, Robert D. Hyldahl, Emma Schaugaard, Mohadeseh Ahmadi Mar 2024

The Effect Of Percussive Massage On Collagen Gene Expression In Skeletal Muscle, James Bartling, Robert D. Hyldahl, Emma Schaugaard, Mohadeseh Ahmadi

Library/Life Sciences Undergraduate Poster Competition 2024

INTRODUCTION

• Exercise is a critical aspect of healthy living due in part to its effects of muscle adaptation, which are largely regulated by alterations in gene expression

• Sedentary behavior can be required by diverse life circumstances, suggesting a need to reproduce the beneficial effects of exercise by an alternative means

• Like exercise, percussive massage introduces a mechanical strain on the muscle, which could potentially replicate a similar remodeling response of the extracellular matrix (ECM). However, this has not yet been studied

• Collagen 1,3,&4 are major components of the ECM that adapt in response to exercise, and …


Staying Hydrated: A Comparative Analysis Of Humectants In Human Tissue, Rachel Prince, Jason Adams, Joseph Monsen Mar 2024

Staying Hydrated: A Comparative Analysis Of Humectants In Human Tissue, Rachel Prince, Jason Adams, Joseph Monsen

Library/Life Sciences Undergraduate Poster Competition 2024

3rd Place Poster Design

Humectants are an important class of compounds that attract and retain water within a cell. When mixed with water to create wetting solutions, humectants can prevent desiccation of cadaveric specimens1. Recognizing a relative scarcity of comparative studies analyzing the effects of various wetting solutions on post-preservation cadaveric maintenance, we utilized wet-dry analysis in order to compare the effects of four common humectants on water retention in human cadaveric tissue including brain, cardiac muscle, liver, lung, skeletal muscle, and skin. We created a concentration gradient for each humectant to identify the optimal concentrations of each compound for …


Jaspine B And The Sea Sponge That Fights Cancer, Jack Davis, Jared Barrott, Adriene Pavek, Farjana Afrin, Sameena Mateen, Brendon Meldrum, Rocio Rojas, Pamela Diaz, Megan Condie, Ali Aghazadeh-Habashi, Srinath Pashikanti Mar 2024

Jaspine B And The Sea Sponge That Fights Cancer, Jack Davis, Jared Barrott, Adriene Pavek, Farjana Afrin, Sameena Mateen, Brendon Meldrum, Rocio Rojas, Pamela Diaz, Megan Condie, Ali Aghazadeh-Habashi, Srinath Pashikanti

Library/Life Sciences Undergraduate Poster Competition 2024

Jaspine B is a natural marine product, derived from the sea sponge, Jaspis, found in some tropical climates. Jaspine B has been shown to be an effective treatment in some cancers with an upregulation of sphingomyelin synthase. This research aimed to understand the effects of Jaspine B on synovial sarcoma, and investigate its potential to be used as targeted treatment in other cancers that have an upregulation of sphingomyelin synthase


Exploring The Role Of Dopamine And Atp In Microglial Motility, Derek Langford, Jordan Yorgas, Christopher Galbraith, Channing Syme, Brayden Parker, Savannah Evans, Derek Langford, Eliza White, Erin Taylor, Lauren Ford, Hillary Wadsworth Mar 2024

Exploring The Role Of Dopamine And Atp In Microglial Motility, Derek Langford, Jordan Yorgas, Christopher Galbraith, Channing Syme, Brayden Parker, Savannah Evans, Derek Langford, Eliza White, Erin Taylor, Lauren Ford, Hillary Wadsworth

Library/Life Sciences Undergraduate Poster Competition 2024

►Recent studies from our laboratory have identified that dopamine and ATP in the Nucleus Accubmens (NAc) are co-released.

►ATP is a chemoattractant for macrophages in general, and microglia specifically, suggesting that dopamine and ATP corelease may function to alter microglia activity.

►The present work characterizes the effects of microglia activation via lipopolysaccharide (LPS) on dopamine terminal function, and the effects of dopamine and ATP on microglia motility.