Open Access. Powered by Scholars. Published by Universities.®

Life Sciences Commons

Open Access. Powered by Scholars. Published by Universities.®

Articles 1 - 2 of 2

Full-Text Articles in Life Sciences

Surface, But Not Age, Impacts Lower Limb Joint Work During Walking And Stair Ascent, Thomas A. Wenzel, Nicholas L. Hunt, Amy E. Holcomb, Clare K. Fitzpatrick, Tyler N. Brown Dec 2023

Surface, But Not Age, Impacts Lower Limb Joint Work During Walking And Stair Ascent, Thomas A. Wenzel, Nicholas L. Hunt, Amy E. Holcomb, Clare K. Fitzpatrick, Tyler N. Brown

Kinesiology Faculty Publications and Presentations

Older adults often suffer an accidental fall when navigating challenging surfaces during common locomotor tasks, such as walking and ascending stairs. This study examined the effect of slick and uneven surfaces on lower limb joint work in older and younger adults while walking and ascending stairs. Fifteen young (18–25 years) and 12 older (>65 years) adults had stance phase positive limb and joint work quantified during walking and stair ascent tasks on a normal, slick, and uneven surface, which was then submitted to a two-way mixed model ANOVA for analysis. The stair ascent required greater limb, and hip, knee, …


Advances In Cartilage Tissue Engineering Using Bioinks With Decellularized Cartilage And Three-Dimensional Printing, Roxanne N. Stone, Jonathon C. Reeck, Julia Thom Oxford Mar 2023

Advances In Cartilage Tissue Engineering Using Bioinks With Decellularized Cartilage And Three-Dimensional Printing, Roxanne N. Stone, Jonathon C. Reeck, Julia Thom Oxford

Biology Faculty Publications and Presentations

Osteoarthritis, a chronic, debilitating, and painful disease, is one of the leading causes of disability and socioeconomic burden, with an estimated 250 million people affected worldwide. Currently, there is no cure for osteoarthritis and treatments for joint disease require improvements. To address the challenge of improving cartilage repair and regeneration, three-dimensional (3D) printing for tissue engineering purposes has been developed. In this review, emerging technologies are presented with an overview of bioprinting, cartilage structure, current treatment options, decellularization, bioinks, and recent progress in the field of decellularized extracellular matrix (dECM)–bioink composites is discussed. The optimization of tissue engineering approaches using …