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Full-Text Articles in Life Sciences

Exploration Of The Range Overlap Between Cynomys Leucurus And Cynomys Ludovicianus, Kenneth D. Choi Dec 2015

Exploration Of The Range Overlap Between Cynomys Leucurus And Cynomys Ludovicianus, Kenneth D. Choi

Honors Theses

The ranges of two species of prairie dogs, Cynomys leucurus and Cynomys ludovicianus, overlap in a narrow area in the western Great Plains in Wyoming. We used GIS software to map their distributions and infer land cover preferences within and on either side of the zone of overlap. In general, both species used habitats in proportion to their availability and did not display strong selection of their expected vegetation types (based on the literature). However, both species of prairie dogs were overrepresented in areas of human settlements and crops, which may indicate that these species prefer human-modified habitats, or perhaps …


L3 Auditory Interneuron Responses To Dual-Frequency Calling Songs In Female Crickets (Acheta Domesticus), Jeong Bin Lee Dec 2015

L3 Auditory Interneuron Responses To Dual-Frequency Calling Songs In Female Crickets (Acheta Domesticus), Jeong Bin Lee

Honors Theses

Female crickets exhibit positive phonotaxis in response to calling songs with specific carrier frequencies (4-5 kHz), syllable periods (SP; 50-70ms), and other parameters. Among a number of ascending prothoracic auditory neurons identified, only L3 has been proposed to be involved in SP selective phonotaxis. L3 responds with selective decrement to 5 kHz stimulus with attractive SPs. Furthermore, L3 is highly tuned to 16 kHz auditory stimulus, which has been correlated with aversive phonotactic behaviors. L3’s cellular responses to simultaneous 16 kHz and 5 kHz stimuli were examined through extracellular recording, thereby further establishing the connection between L3’s selective decrement and …


Anticancer Activity Of Some Boronic Acid Arylidene Heterocycles, Joy Kim Nov 2015

Anticancer Activity Of Some Boronic Acid Arylidene Heterocycles, Joy Kim

Honors Theses

This research was done in order to investigate the anticancer activity of boronic acid arylidene heterocycles. Boronic acid, heterocycles, and aryl compounds have all independently exhibited various anti-microbial properties and have shown potential to be used in pharmaceuticals for the treatment of viruses and cancers. Using a one-step protocol developed by Dr. Murray, several different arylheterocyclic compounds were combined with an arylboronic acid to synthesize novel compounds. These were then tested for their anti-cancer activity on glioblastoma brain cancer cells. Although varied in potency, all had some amount of anti-cellular effect on the cancer cells. This is only the start …


Paper-Based Biosensor For Colorimetric Detection Of Psa Biomarker, Alyson Drew Jan 2015

Paper-Based Biosensor For Colorimetric Detection Of Psa Biomarker, Alyson Drew

Honors Theses

Prostate cancer is commonly screened in the bloodstream by detection of excess PSA, prostate-specific antigen which is a protein in the prostate produces in large quantities when cancerous tumors are present. In order to facilitate inexpensive and disposable detection, diagnostic tools have begun to be created out of paper and wax which wick solutions through channels based on their hydrophobicity. George M. Whitesides, who pioneered the majority of this work, designed a paper-based LFD, lateral flow device, effective for detecting liver function which we are modifying to detect PSA. In this paper, we designed an oPAD, origami paper analytical device, …