Life Sciences Commons^™

Protozoan Vaccine Candidate Homologues In Tetrahymena Thermophila, Justin Schumacher

Senior Honors Projects

Tetrahymena thermophila is a member of the phylum Ciliophora (the ciliated protozoa) and is currently of great interest due to its unique qualities that make it useful as a model for research directed towards understanding how eukaryotic cells function. Recently, the T. thermophila genome was sequenced, and made available online. Since Tetrahymena is a member of the Alveolata, the major eukaryotic clade that also contains the apicomplexan parasites that cause a number of serious human and animal diseases, we sought to determine whether the genes coding for apicomplexan vaccine candidates were represented in the genome of Tetrahymena. In addition, we …