Life Sciences Commons^™

The Relationship Between Socioeconomic Status And Physical Activity Among Adolescents, Meredith Laurel Stockie

Theses and Dissertations (Comprehensive)

Background: Many Canadian youth are inactive (Active Healthy Kids Canada, 2009). Socioeconomic status (SES) is one factor that influences youth physical activity (PA) levels; however, the factors involved in this relationship are not well understood. Given that numerous quantitative studies suggest there is a positive relationship between SES and PA among adolescents, but offer little insight into why the given relationship exists, the purpose of the current thesis is to study the factors that influence the relationship between SES and PA among youth aged 12–14 years through a qualitative lens.

Methods: Low (n = 2) and high SES (n = …

The Influence Of Propyl Pyrazole Triol On The Post-Exercise Alpha Estrogen Receptor-Mediated Activation Of Satellite Cells In Skeletal Muscle Of Ovariectomized Rats, Amy Elisabeth Thomas

Theses and Dissertations (Comprehensive)

Estrogen has been shown to augment satellite cell activation, proliferation and total number and that this may occur through an estrogen receptor (ER) mediated mechanism. The purpose of this study was to investigate the role of ERs in the postexercise estrogen-induced augmentation of satellite cells in skeletal muscle of ovariectomized rats. Furthermore, the specific role of the ERα was examined through the use of an ERa agonist, propyl pyrazole triol (PPT). Ovariectomized rats were used (n=64) and separated into 4 groups: sham, estrogen supplemented, agonist supplemented and a combined estrogen and agonist supplemented group. These groups were further subdivided into …

Inference, Orthology, And Inundation: Addressing Current Challenges In The Field Of Metagenomics, Gregory Detlev Alexander Vey

Theses and Dissertations (Comprehensive)

The vast increase in the number of sequenced genomes has irreversibly changed the landscape of the biological sciences and has spawned the current post-genomic era of research. Genomic data have illuminated many adaptation and survival strategies between species and their habitats. Moreover, the analysis of prokaryotic genomic sequences is indispensible for understanding the mechanisms of bacterial pathogens and for subsequently developing effective diagnostics, drugs, and vaccines. Computational strategies for the annotation of genomic sequences are driven by the inference of function from reference genomes. However, the effectiveness of such methods is bounded by the fractional diversity of known genomes. Although …

Metabolic And Molecular Approaches To The Study Of Bacterial Communities In Wetlands Of The Alberta Athabasca Oil Sands Region, Jessica Dawn Morrison

Theses and Dissertations (Comprehensive)

Bacterial communities in wetlands from the Athabasca region (Alberta, Canada) were surveyed and their utility as bio-indicators for wetland reclamation was assessed. Sediment samples were collected from wetlands categorized as: (1) natural (off mining leases), (2) reference (on mining sites but not directly impacted by oil sands processed material (OSPM)), and (3) OSPM (directly affected by OSPM). Wetlands of the latter two groups ranged in age from 11 to 24 years. Analysis involved community level physiological profiling (CLPP) with BIOLOG™ EcoPlates, and denaturing gradient gel electrophoresis (DGGE). Multivariate analysis applied to data from both techniques revealed differences in the bacterial …

An Examination Of Intercollegiate Athletic Injury Tracking Systems Within Canadian Universities, Andrew D. Ross

Theses and Dissertations (Comprehensive)

Information regarding the practice of athletic injury tracking within Canadian intercollegiate institutions has been relatively deficient. The study aimed to assess the current status of athletic injury tracking systems (AITS) in Canadian universities within the Canadian Interuniversity Sport Association (CIS). A secondary purpose was to obtain data from therapists within Canadian Universities, to identify and analyze issues, benefits, barriers and obtain information regarding how athletic injury tracking methods are conducted. This was achieved by obtaining data regarding the current state of AITS in CIS institutions, clinical demographics, athletic therapists and/or physiotherapists’ opinions regarding the pro’s and con’s of athletic injury …

Evolution And Systematic Significance Of Reproductive Structures In The Genus Cuscuta (Dodders, Convolvulaceae): Pollen And Gynoecium, Mark Welsh

Theses and Dissertations (Comprehensive)

The genus Cuscuta (dodders, Convolvulaceae) is one of the most significant lineages of parasitic plants from economic, conservation, and anthropogenic perspectives. Members of the genus are twining stem parasites with no roots, lacking almost completely chlorophyll or its function, and gather required nutrition from their host via specialized haustorial connections. While there are almost 200 described species, problems with species identification exist because many diagnostic characters are restricted to their tiny flowers. Probably contributing to this identification difficulty is the fact that the group has not received taxonomic attention for over 75 years; even knowledge of its basic reproductive biology …

The Influence Of Concurrent Visual Feedback During Treadmill Training In Parkinson’S Disease, Rose Ellen Johnston

Theses and Dissertations (Comprehensive)

Walking is an exercise that has been thought to benefit Parkinson’s disease (PD). In a laboratory setting treadmills have been employed to successfully improve certain aspects of gait in PD (Cakit et al., 2007, Fisher et al., 2008, Herman et al., 2007, Miyai et al., 2000, Miyai et al., 2002, Pohl et al., 2003). Research has also indicated that walking with visual cues can improve aspects of gait that are impaired in PD (Azulay et al., 1999, Bagely et al., 1997, Nieuwboer et al., 2007), however, the integration of visual cues and treadmill training has yet to be studied. Thus, …

Mechanism(S) Of 3-Trifluoromethyl-4-Nitrophenol (Tfm) Toxicity In Sea Lamprey (Petromyzon Marinus) & Rainbow Trout (Oncorhynchus Mykiss), Oana Birceanu

Theses and Dissertations (Comprehensive)

The pesticide, 3-trifluoromethyl-4-nitrophenol (TFM), has been extensively used over the last 50 years to control invasive sea lamprey (P. marinus) populations in the Great Lakes, but its mechanism of toxicity is unresolved. Due to its structural similarity to phenolic compounds known to inhibit mitochondrial ATP production, one hypothesis on the mode of action of TFM is that it impairs mitochondrial oxidative phosphorylation. A second hypothesis is that TFM targets the gill, interfering with gill ion uptake. Exposure of larval sea lamprey and rainbow trout (O. mykiss), to each animal’s respective 12-h TFM LC50, resulted in marked …

Effects Of Estrogen Receptor Activation On Post-Exercise Muscle Satellite Cell Proliferation, Kareem Bunyan

Theses and Dissertations (Comprehensive)

This study investigated the role of estrogen receptor activation on total and proliferating satellite cells following running exercise in rats, by using an estrogen receptor-alpha (ER-α) specific agonist, 4,4,4 (4-Propyl-[1H]-pyrazole-1,3,5-triyl) trisphenol (PPT). PPT is the first ER-α specific agonist (Stauffer et al 2000) which binds the ER-a subtype with a 410-greater affinity than ER-β (Stauffer et al 2000). Previous studies have demonstrated that estrogen can augment muscle satellite cell numbers following exercise (Enns and Tiidus, 2008) and that this augmentation may be due to mechanisms activated via estrogen receptors that can influence total, proliferating, and differentiating satellite cell numbers (Enns …

A Study Of The Waterborne And Dietary Toxicityof Cadmium To Hydra Attenuata And Daphnia Plux In Soft Waters And The Development Of Biotic Ligand Models To Predict Such Toxicity, Matthew S.A. Clifford

Theses and Dissertations (Comprehensive)

The goal of this thesis was to compare the effects of waterborne Cd exposures and dietary Cd exposures to Hydra attenuata. Before the Hydra could be exposed to dietborne exposures of Cd, the effects of waterborne exposures had to be understood. This was done by looking at the sensitivity of D. pulex to Cd and then understanding the accumulation of Cd. After bioaccumulation patterns of Cd. to D. pulex were known, we could then feed the prey to the Hydra and comapre the effects to waterborne effects of Cd to Hydra.

To understand the waterborne effects of Cd to …

Population Density, Circulating Testosterone And Dawn Chorus Behaviour In White-Throated Sparrows (Zonotrichia Albicollis), Simon Richard Hall

Theses and Dissertations (Comprehensive)

An integrative approach to biological research has facilitated the study not only of specific phenomena, but of the connections between these phenomena. A particularly striking example is that of the relationships between testosterone, social behavior, and social context. Increased levels of testosterone increase the frequency of aggressive behaviors and reduce the quality of parental care in many songbird species, and these changes in behavior can affect the surrounding social environment. Different social contexts, population density as a readily studied example, affect the cues that control the release of testosterone into the bloodstream. The distinct tan-stripe and white-stripe phenotypic morphs of …

Using Chemical, Optical And Biological Methods To Characterize Cu Complexation By Different Natural Organic Matter Sources Collected From Canadian Shield Waters, Keegan Andrew Hicks

Theses and Dissertations (Comprehensive)

The effects of natural organic matter (NOM) source on Cu complexation were characterized chemically, optically and biologically in soft waters. NOM from different Canadian Shield soft water lakes were concentrated using reverse osmosis and for comparison NOM was also sampled from a hard water source. NOM complexation capacity was assessed directly in Cu spiked solutions (with and without additions of NOM) by measuring free Cu activity using an ion selective electrode. Additional chemical and optical characterizations of NOM included specific absorbance coefficient (SAC; at 340 nm), excitation-emission matrix spectroscopy, protein content, and molecular weight fractionation (fraction of DOCkDa). The biological …

Piecing Together The Puzzle Of Autism: Aspects Of Its Effects On Children With The Condition And Their Caregivers, Roula Markoulakis

Theses and Dissertations (Comprehensive)

As one of the most prevalent developmental disorders, extensive research exists concerning Autism Spectrum Disorders (ASD). However, gaps are still evident in a number of areas. Information pertaining to any costs and benefits associated with the experience of caring for a child with autism is inadequate. In Study 1, the lived experiences of married female primary caregivers of children with autism were explored, specifically by examining the costs and benefits of caregiving and its influence on the women’s situations. Furthermore, motor control deficits are apparent in many children with high functioning autism (HFA) and Asperger syndrome (AS), but need to …

Characterization Of The Interaction Between Arabidopsis Toc159 And Toc33 Gtpase Domains, Wesley A. Farquharson

Theses and Dissertations (Comprehensive)

Protein-protein interactions are critical for many biochemical processes and for cellular function. Understanding interactions between proteins and ligands, as well as other proteins are necessary for the modelling of biological systems. Protein import into chloroplasts is one such system where the understanding of interactions between members of the translocation complex is limited. The translocon at the outer envelope membrane of chloroplasts (Toe complex) consists of three core components: Toc75, Tocl59, and Toc34. Members of the Tocl59 and Toc34 gene families in Arabidopsis thaliana have been shown to assemble differentially into structurally and functionally distinct complexes. More specifically, there is evidence …