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Full-Text Articles in Life Sciences
West-Nile Virus Replicon Particles Infect 293t Cells Expressing Dc-Signr, Osvaldo Martinez, Emin Budimlic, John Keilty, Hannah Kunkel, Wells Pollock, Madilyn R. Schmitz, Nicole Crowson, Nathan L. Leonard, Amanda Madigan, Victoria R. Schwarzinger, Alyssa J. Meyer, Mary Soderlund, Jean K. Lim, Icann School Of Medicine, New York
West-Nile Virus Replicon Particles Infect 293t Cells Expressing Dc-Signr, Osvaldo Martinez, Emin Budimlic, John Keilty, Hannah Kunkel, Wells Pollock, Madilyn R. Schmitz, Nicole Crowson, Nathan L. Leonard, Amanda Madigan, Victoria R. Schwarzinger, Alyssa J. Meyer, Mary Soderlund, Jean K. Lim, Icann School Of Medicine, New York
Undergraduate Research Celebration 2018
West-Nile virus (WNV) is an arbovirus usually transmitted to humans via a mosquito vector. Infections commonly result in febrile symptoms while rare severe neuroinvasive cases may result in encephalitis or meningitis. Studies have shown that WNV infection efficiency is enhanced by expression of DC-SIGNR on target cells, which normally do not express DC-SIGNR. To investigate WNV tropism, we established 293T kidney epithelial cell lines that stably express vector, DC-SIGNR and mutants of DC-SIGNR that lack the entire carbohydrate-recognition domain (CRD) or lack the C-terminal half of the CRD. We demonstrate successful surface expression of DC-SIGNR and its mutants from stablytransfected …
Research Of White Sucker Cell Lines And Associated Viruses, Mohamed Mohamed, Casey M. Finnerty
Research Of White Sucker Cell Lines And Associated Viruses, Mohamed Mohamed, Casey M. Finnerty
Undergraduate Research Celebration 2018
Catostomus commersonii, also known as the White Sucker, is a vital part of most aquatic ecosystems in the U.S. Specifically looking at the Upper Midwest, these fish are widely distributed around the states of Minnesota and Wisconsin. The importance of these organisms is due to their species reputation, they are indicator species that are very useful in informing whether the environment around them is healthy or if contamination has occurred. To better understand the organism, we needed to start at the molecular level. Understanding the nature of White Sucker cells through cell cultures. To get the individual fins of the …
The Impact Of Urbanization On Mosquito-Borne Viruses, Nikhita Puthuveetil
The Impact Of Urbanization On Mosquito-Borne Viruses, Nikhita Puthuveetil
Undergraduate Research Posters
Mosquito-borne diseases such as yellow fever, dengue, and West Nile are rapidly emerging across the globe. Their emergence is often aided by the growth of their vector population, or the organisms that transmit the virus to the host. Urbanization and land use often destroys the habitat of the virus and its vector. However, the virus and its vector often survive despite the changes to its environment. The goal of this paper is to find out exactly how urbanization and changes in land use affect mosquito-borne viruses and how these viruses survive despite the destruction of their habitats. To understand how …