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Full-Text Articles in Life Sciences
Nup211 Plays An Important Role In Regulating Mrna Export And Stress Response, Ayana Ikenouchi
Nup211 Plays An Important Role In Regulating Mrna Export And Stress Response, Ayana Ikenouchi
Theses and Dissertations
Nup211 is a nuclear pore basket component in Schizosaccharomyces pombe and roles in the gating functions of NPCs. Using RT-qPCR, I found that in nup211-shutoff cells, the transcript levels of genes in mRNA export and stress-response pathways were significantly changed, suggesting nup211 is involved in regulating stress response pathways.
Cytotoxic Analysis Of Old Drugs: New Drugs For Alzheimer’S Disease, Sebastian Yumiseba
Cytotoxic Analysis Of Old Drugs: New Drugs For Alzheimer’S Disease, Sebastian Yumiseba
Theses and Dissertations
Microglia are the resident immune cells of the CNS and constitute about 10% of all cells in the CNS. They have a vital role in Alzheimer’s pathogenesis as either cytotoxic or neuroprotective. Recent efforts are being put into repurposing drugs to target the microglia to treat Alzheimer’s disease.
Pvt1 Exon 9 A Regulator Of Claudin Expression In Triple Negative Breast Cancer, Fayola Levine
Pvt1 Exon 9 A Regulator Of Claudin Expression In Triple Negative Breast Cancer, Fayola Levine
Theses and Dissertations
Claudin low triple negative breast cancer (TNBC) has the worst clinical outcomes in comparison to other breast cancer subtypes. The underlying molecular mechanisms associated with the aberrant expression of claudins are not well understood. The transcript from PVT1 exon 9 is a regulator of claudin expression, and migration, in TNBC.
How The Egg Rolls: A Morphological Analysis Of Egg Shape In The Context Of Displacement Dynamics, Ian R. Hays
How The Egg Rolls: A Morphological Analysis Of Egg Shape In The Context Of Displacement Dynamics, Ian R. Hays
Theses and Dissertations
Very little is known about how morphology effects the motion, stability and the resulting viability of avian eggs. The limited research that exists focuses on the pyriform or ‘pointed’ egg shapes found in the Alcidea family. This unusual shell form is thought to suppress displacement and prevents egg loss on the cliffside nesting habitat of the Uria genera. Unfortunately, these studies never isolated or quantify the specific morphological features (elongation, asymmetry and conicality) of these pyriform eggs, which limits their applicability to other taxa and hampers a robust proof of concept. We isolated each feature as a variable, produced models …