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Full-Text Articles in Life Sciences
In Vitro Antioxidants And Anticancer Activity Of Crude Extract Isolates From Euphorbiaceae In Northern Thailand, Siwalee Rattanapunya, Wiriyaporn Sumsakul, Akharasit Bunsongthae, Samart Jaitia
In Vitro Antioxidants And Anticancer Activity Of Crude Extract Isolates From Euphorbiaceae In Northern Thailand, Siwalee Rattanapunya, Wiriyaporn Sumsakul, Akharasit Bunsongthae, Samart Jaitia
The Thai Journal of Pharmaceutical Sciences
The properties of Croton persimilis Müll.Arg. and Antidesma puncticulatum Miq.— interesting plant in the family Euphorbiaceae were investigated. The ethanol crude plant extracts were established for phytochemicals screening, antioxidants activities, anticancer in five important human cancer cell lines (MCF-7, MDA-MB-231, HeLa, HepG2, and NCI-H187), and cytotoxic activity in normal cell line (hTERT-HME1). The leaves extracts of C. persimilis Müll. Arg. contained flavonoids, saponins, terpenoids, and tannins. The total phenolic content properties were found in 43.40 ± 1.36 mg Gallic Acid Equivalents (GAE)/g crude extract. They also showed lowest antioxidant activity through 2, 2-diphenyl-1-picrylhydrazyl (DPPH) assay (IC50>1,000 μg/ml) and 2.4.2 …
Pharmacognostic And Chromatographic Evaluation Of Male And Female Flowers Of Coscinium Fenestratum For Berberine Content And Its Effect On Antioxidant Activity, T. S. Roopashree, Kuntal Das, N. Prashanth, K. Rakesh Kumar
Pharmacognostic And Chromatographic Evaluation Of Male And Female Flowers Of Coscinium Fenestratum For Berberine Content And Its Effect On Antioxidant Activity, T. S. Roopashree, Kuntal Das, N. Prashanth, K. Rakesh Kumar
The Thai Journal of Pharmaceutical Sciences
Coscinium fenestratum (CF) (Gaertn.) Colebr., [Family: Menispermaceae] is an endangered species of dioecious liana found in Western Ghats of India. The present investigation aimed with systematic analytical studies on the macroscopic, microscopic examination of male and female CF flowers, various solvent extractions, accompanied by phytochemical screening through chemical tests, identification of Berberine alkaloids, antioxidant activity, and Berberine quantification byhigh-performance thin-layer chromatography (HPTLC) process. Two different amounts of solvents (10 ml and 20 ml) with two different time intervals, that is, 15 min and 25 min, respectively, were used for extraction. Results revealed that both flowers had their own unique characters. …
Synthesis, Evaluation, And In Silico Studies Of 2-Mercapto-5-Substituted Styryl-1,3,4-Oxadiazoles As Potential Cytotoxic Agents, Anitha Kumari Vinjavarapu, Shaheen Begum, Bharathi Koganti
Synthesis, Evaluation, And In Silico Studies Of 2-Mercapto-5-Substituted Styryl-1,3,4-Oxadiazoles As Potential Cytotoxic Agents, Anitha Kumari Vinjavarapu, Shaheen Begum, Bharathi Koganti
The Thai Journal of Pharmaceutical Sciences
Objective: The objective of the present study is to design, synthesize and evaluate 2-mercapto-5-styryl-1,3,4-oxadiazoles with an aim of developing potential cytotoxic agents and to carryout in silico studies to understand the possible interactions with .
In Vitro Biological Activities Of Black Pepper Essential Oil And Its Major Components Relevant To The Prevention Of Alzheimer’S Disease, Pattamapan Lomarat, Kittisak Sripha, Phanida Phanthong, Worawan Kitphati, Krit Thirapanmethee, Nuntavan Bunyapraphatsara
In Vitro Biological Activities Of Black Pepper Essential Oil And Its Major Components Relevant To The Prevention Of Alzheimer’S Disease, Pattamapan Lomarat, Kittisak Sripha, Phanida Phanthong, Worawan Kitphati, Krit Thirapanmethee, Nuntavan Bunyapraphatsara
The Thai Journal of Pharmaceutical Sciences
Black pepper oil and its major components were investigated for the biological activities related to the prevention of AD. The inhibition of acetylcholinesterase (AChE) and β-amyloid aggregation, anti-inflammatory and antioxidant activities were examine...
Phytofabrication Of Silver Nanoparticles Using Horse Gram (Dolichos Biflorus L.) Seed Extract And Assessment Of Its Bactericidal And Antioxidant Activities, Mahadevan Vijayalakshmi, Thangavel Rajagopal, Jeyachandran Vijayakumar, Ponnirul Ponmanickam
Phytofabrication Of Silver Nanoparticles Using Horse Gram (Dolichos Biflorus L.) Seed Extract And Assessment Of Its Bactericidal And Antioxidant Activities, Mahadevan Vijayalakshmi, Thangavel Rajagopal, Jeyachandran Vijayakumar, Ponnirul Ponmanickam
The Thai Journal of Pharmaceutical Sciences
The silver nanoparticles synthesized by phytofabrication method receive bigger attention due to their fascinating properties. This study deals with the green mediated synthesis of silver nanoparticles using seed extract of horse gram (Dolichos biflorus L...
Antioxidant Activity, Phenolic Compound Contents And Antimutagenic Activity Of Some Water Extract Of Herbs, Kalyarat Mekaroonreung, Kaew Kangsadalampai
Antioxidant Activity, Phenolic Compound Contents And Antimutagenic Activity Of Some Water Extract Of Herbs, Kalyarat Mekaroonreung, Kaew Kangsadalampai
The Thai Journal of Pharmaceutical Sciences
Ten water extracts from herbs were prepared by boiling in hot water for 10 min. The herbal extracts were studied for their antioxidant activity and phenolic compound contents. In this study, the extracts of C arthamus tinctorius L, Hibiscus sabdariffa L,...