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Full-Text Articles in Life Sciences
Recent Advances In X-Ray Microanalysis In Dermatology, Bo Forslind, Thomas G. Grundin, Magnus Lindberg, Godfried M. Roomans, Ylva Werner
Recent Advances In X-Ray Microanalysis In Dermatology, Bo Forslind, Thomas G. Grundin, Magnus Lindberg, Godfried M. Roomans, Ylva Werner
Scanning Electron Microscopy
Electron microprobe and proton microprobe X-ray analysis can be used in several areas of dermatological research. With a proton probe, the distribution of trace elements in human hair can be determined. In contrast to sulfur, which is homogeneously distributed, calcium, iron, and zinc appear to be non-homogeneously distributed over the hair cross-section.
Electron microprobe analysis on freeze-dried cryosections of guinea-pig and human epidermis shows a marked gradient of Na, P and K over the stratum granulosum. In sections of freeze-substituted human skin this gradient is less steep. This difference is likely to be due to a decrease in water content …
The Application Of Physico-Chemical Procedures In The Analysis Of Urinary Calculi, Allen L. Rodgers
The Application Of Physico-Chemical Procedures In The Analysis Of Urinary Calculi, Allen L. Rodgers
Scanning Electron Microscopy
All physico-chemical techniques used in the analysis of urinary calculi have inherent advantages and limitations. Al though x-ray powder diffraction can identify constituents unambiguously, certain minor components can be missed. Infrared spectroscopy is more sensitive but band assignment at low concentrations is difficult. Scanning electron microscopy together with energy dispersive x-ray analysis permits the simultaneous investigation of morphology and chemical microstructure. However, microanalysis of elements lighter than sodium is not possible and constituents are prone to irradiation damage. With the electron microprobe, minor constituents can be detected but tedious sample preparation procedures are required. Transmission electron microscopy is extremely useful …
Microprobe Analysis In Human Pathology, D. Baker, K. G. Kupke, P. Ingram, V. L. Roggli, J. D. Shelburne
Microprobe Analysis In Human Pathology, D. Baker, K. G. Kupke, P. Ingram, V. L. Roggli, J. D. Shelburne
Scanning Electron Microscopy
This tutorial paper reviews the literature on the application of microprobe analysis to practical problems in diagnostic human pathology. The goal is to allow the reader ready access to the literature on specific clinical problems. Specimen preparation and commonly encountered artifacts are also considered. It is concluded that energy dispersive x-ray microanalysis and backscattered electron imaging are at present the most generally useful microprobe techniques for clinical work, and are no longer solely research tools. The findings often have diagnostic, therapeutic, and/or legal implications.