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Full-Text Articles in Life Sciences

Whole Tart Cherry Improves Disease Activity Index In Rat Model Of Dextran Sulfate Solution – Induced Ulcerative Colitis By Downregulating The Janus 1 And Janus 3 Kinases And Tnf - Alpha, Johana Alexandra Coronel Apr 2018

Whole Tart Cherry Improves Disease Activity Index In Rat Model Of Dextran Sulfate Solution – Induced Ulcerative Colitis By Downregulating The Janus 1 And Janus 3 Kinases And Tnf - Alpha, Johana Alexandra Coronel

LSU Master's Theses

Ulcerative colitis (UC) is a disabling inflammatory bowel disease. UC is characterized by chronic, relapsing inflammation of the colon and rectum. Current treatments such as monoclonal antibodies against TNF-α, IL-6, IL-12/p40, adhesion molecules, Janus kinases (JAK) inhibitors have side effects or lose their effects over time. Alternative approaches with fewer side effects for patients are needed. Montmorency tart cherries (Prunus cerasus) are a good source of anti-inflammatory flavonoids. We hypothesized that regular consumption whole tart cherry (TC) standardized to its major anthocyanin content, namely cyanidin-3-glucosyl-rutinoside, would be effective in reducing inflammation in UC. The aim of this research was to …


In Vitro Inhibitory Activity Of Black Seed Oil And Potassium Chloride Against The Biomarkers Of Triple Negative Breast Cancer, Tamaratina Jombai Jan 2011

In Vitro Inhibitory Activity Of Black Seed Oil And Potassium Chloride Against The Biomarkers Of Triple Negative Breast Cancer, Tamaratina Jombai

LSU Master's Theses

Breast cancer is the leading cause of death among women and is highly heterogeneous in nature. One very aggressive subtype of this disease is Triple Negative Breast Cancer. Triple Negative Breast Cancer (TNBC), is a very aggressive disease characterized by the lack of expression of estrogen receptors (ER), progesterone receptors (PR) and human epidermal growth factor receptor-2 (HER-2). TNBC patients account for approximately 15% of total breast cancer patients. This breast cancer subtype is characterized by high mortality rate, and is typically associated with poor prognosis. Current clinical methods have proven to have low success rates against TNBC, it is …