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2019

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A Trial Sequential Meta-Analysis Of Tnf-Α –308g>A (Rs800629) Gene Polymorphism And Susceptibility To Colorectal Cancer, Raju K. Mandal, Munawwar Ali Khan, Arif Hussain, Naseem Akhter, Arshad Jawed, Sajad A. Dar, Mohd Wahid, Aditya K. Panda, Mohtashim Lohani, Bhartendu N. Mishra, Shafiul Haque Jan 2019

A Trial Sequential Meta-Analysis Of Tnf-Α –308g>A (Rs800629) Gene Polymorphism And Susceptibility To Colorectal Cancer, Raju K. Mandal, Munawwar Ali Khan, Arif Hussain, Naseem Akhter, Arshad Jawed, Sajad A. Dar, Mohd Wahid, Aditya K. Panda, Mohtashim Lohani, Bhartendu N. Mishra, Shafiul Haque

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© 2019 The Author(s). Purpose: Tumor necrosis factor-α (TNF-α), secreted by the activated macrophages, may participate in the onset and progression of colorectal cancer (CRC). The association of TNF-α –308 G>A (rs1800629) single-nucleotide polymorphism (SNP) with CRC risk has been investigated by many studies but the results are inconclusive. A trial sequential meta-analysis was performed for precise estimation of the relationship between TNF-α –308 G>A gene polymorphism with CRC risk. Methods: Medline (PubMed), EMBASE (Excerpta-Medica) and Google Scholar were mined for relevant articles. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the significance of …


Development And Validation Of A Prediction Model For Fat Mass In Children And Adolescents: Meta-Analysis Using Individual Participant Data, Mohammed T. Hudda, Mary S. Fewtrell, Dalia Haroun, Sooky Lum, Jane E. Williams, Jonathan C.K. Wells, Richard D. Riley, Christopher G. Owen, Derek G. Cook, Alicja R. Rudnicka, Peter H. Whincup, Claire M. Nightingale Jan 2019

Development And Validation Of A Prediction Model For Fat Mass In Children And Adolescents: Meta-Analysis Using Individual Participant Data, Mohammed T. Hudda, Mary S. Fewtrell, Dalia Haroun, Sooky Lum, Jane E. Williams, Jonathan C.K. Wells, Richard D. Riley, Christopher G. Owen, Derek G. Cook, Alicja R. Rudnicka, Peter H. Whincup, Claire M. Nightingale

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© Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to. To develop and validate a prediction model for fat mass in children aged 4-15 years using routinely available risk factors of height, weight, and demographic information without the need for more complex forms of assessment. Design Individual participant data meta-analysis. Setting Four population based cross sectional studies and a fifth study for external validation, United Kingdom. Participants A pooled derivation dataset (four studies) of 2375 children and an external validation dataset of 176 children with complete data on …