Open Access. Powered by Scholars. Published by Universities.®
Articles 1 - 1 of 1
Full-Text Articles in Life Sciences
Calcium Signaling In The Ventricular Myocardium Of The Goto-Kakizaki Type 2 Diabetic Rat, L. Al Kury, M. Smail, M. A. Qureshi, V. Sydorenko, A. Shmygol, M. Oz, J. Singh, F. C. Howarth
Calcium Signaling In The Ventricular Myocardium Of The Goto-Kakizaki Type 2 Diabetic Rat, L. Al Kury, M. Smail, M. A. Qureshi, V. Sydorenko, A. Shmygol, M. Oz, J. Singh, F. C. Howarth
All Works
© 2018 L. Al Kury et al. The association between diabetes mellitus (DM) and high mortality linked to cardiovascular disease (CVD) is a major concern worldwide. Clinical and preclinical studies have demonstrated a variety of diastolic and systolic dysfunctions in patients with type 2 diabetes mellitus (T2DM) with the severity of abnormalities depending on the patients' age and duration of diabetes. The cellular basis of hemodynamic dysfunction in a type 2 diabetic heart is still not well understood. The aim of this review is to evaluate our current understanding of contractile dysfunction and disturbances of Ca2+ transport in the Goto-Kakizaki …