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University of Kentucky

2021

Antibiotic resistance

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Full-Text Articles in Life Sciences

Effect Of Biochanin A On The Rumen Microbial Community Of Holstein Steers Consuming A High Fiber Diet And Subjected To A Subacute Acidosis Challenge, Brittany E. Harlow, Michael D. Flythe, James L. Klotz, David L. Harmon, Glen E. Aiken Jul 2021

Effect Of Biochanin A On The Rumen Microbial Community Of Holstein Steers Consuming A High Fiber Diet And Subjected To A Subacute Acidosis Challenge, Brittany E. Harlow, Michael D. Flythe, James L. Klotz, David L. Harmon, Glen E. Aiken

Animal and Food Sciences Faculty Publications

Subacute rumen acidosis (SARA) occurs when highly fermentable carbohydrates are introduced into the diet, decreasing pH and disturbing the microbial ecology of the rumen. Rumen amylolytic bacteria rapidly catabolize starch, fermentation acids accumulate in the rumen and reduce environmental pH. Historically, antibiotics (e.g., monensin, MON) have been used in the prevention and treatment of SARA. Biochanin A (BCA), an isoflavone produced by red clover (Trifolium pratense), mitigates changes associated with starch fermentation ex vivo. The objective of the study was to determine the effect of BCA on amylolytic bacteria and rumen pH during …