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Full-Text Articles in Life Sciences
Development Of An Alphavirus Replicon Classical Swine Fever Virus Vaccine Candidate, J. Dustin Loy, Mark Mogler, Jill Gander, Kurt I. Kamrud, D.L. Hank Harris
Development Of An Alphavirus Replicon Classical Swine Fever Virus Vaccine Candidate, J. Dustin Loy, Mark Mogler, Jill Gander, Kurt I. Kamrud, D.L. Hank Harris
John Loy
Classical swine fever virus (CSFV) E2 glycoprotein was expressed in an alphavirus based replicon expression system. Vaccinated pigs developed CSFV-specific antibodies. This is the first known use of this technology against CSFV.
Evaluation Of Double Stranded Rna For The Prevention Of Infectious Myonecrosis Virus (Imnv) In Litopenaeus Vannamei, J. Dustin Loy, Lyric C. Bartholomay, D. L. Hank Harris
Evaluation Of Double Stranded Rna For The Prevention Of Infectious Myonecrosis Virus (Imnv) In Litopenaeus Vannamei, J. Dustin Loy, Lyric C. Bartholomay, D. L. Hank Harris
John Loy
Double stranded RNA was synthesized in vitro with sequences corresponding to portions of the IMNV genome and were injected into shrimp prior to challenge with IMNV. This is the first time these methods have been used to prevent IMN in shrimp.
Experimental Transmission Of Necrotizing Hepatopancreatitis Bacteria To Post-Larval Litopeneaus Vannamei, J. Dustin Loy, D. L. Hank Harris
Experimental Transmission Of Necrotizing Hepatopancreatitis Bacteria To Post-Larval Litopeneaus Vannamei, J. Dustin Loy, D. L. Hank Harris
John Loy
Day 15 specific pathogen free Post-Larval Pacific White Shrimp, Litopeneaus vannamei, were infected with Necrotizing Hepatopancreatitis bacteria (NHPB) by per os exposure. This is the first documented report of controlled post larval (PL) infection and mortality with NHPB.
Development And Evaluation Of A Replicon Particle Vaccine Expressing The E2 Glycoprotein Of Bovine Viral Diarrhea Virus (Bvdv) In Cattle, John Dustin Loy, Jill Gander, Mark Mogler, Ryan Vander Veen, Julia Ridpath, Delbert Hank Harris, Kurt Kamrud
Development And Evaluation Of A Replicon Particle Vaccine Expressing The E2 Glycoprotein Of Bovine Viral Diarrhea Virus (Bvdv) In Cattle, John Dustin Loy, Jill Gander, Mark Mogler, Ryan Vander Veen, Julia Ridpath, Delbert Hank Harris, Kurt Kamrud
John Loy
Background: Bovine viral diarrhea virus is one of the most significant and costly viral pathogens of cattle worldwide. Alphavirus-derived replicon particles have been shown to be safe and highly effective vaccine vectors against a variety of human and veterinary pathogens. Replicon particles are non-propagating, DIVA compatible, and can induce both humoral and cell mediated immune responses. This is the first experiment to demonstrate that Alphavirus-based replicon particles can be utilized in a standard prime/boost vaccination strategy in calves against a commercially significant bovine pathogen. Findings: Replicon particles that express bovine viral diarrhea virus sub-genotype 1b E2 glycoprotein were generated and …
Evaluation Of In Vivo Hemocyte Phagocytosis Of Microsphere Beads In Litopenaeus Vannamei Utilizing Flow Cytometry Following Administration Of Bacterial Lipopolysaccharides, J. Dustin Loy, D. L. Hank Harris
Evaluation Of In Vivo Hemocyte Phagocytosis Of Microsphere Beads In Litopenaeus Vannamei Utilizing Flow Cytometry Following Administration Of Bacterial Lipopolysaccharides, J. Dustin Loy, D. L. Hank Harris
John Loy
Carboxylate modified microspheres were injected into shrimp and phagocytosis of these particles was measured using flow cytometry following treatment with microbial lipopolysaccharides. This is the first time these methods have been used to assess innate immune responses in shrimp