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James Madison University

Masters Theses, 2020-current

Postprandial

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Postprandial Exhaled Nitric Oxide Responses In Older And Younger Adults With And Without Acute Exercise, Molly Miller May 2021

Postprandial Exhaled Nitric Oxide Responses In Older And Younger Adults With And Without Acute Exercise, Molly Miller

Masters Theses, 2020-current

A single high fat meal (HFM) increases airway inflammation in young, healthy individuals. Additionally, aging increases airway resistance and inflammation, though the airway inflammatory response to a HFM has not been investigated. Exercise is a natural anti-inflammatory, but has yet to be administered with a HFM as a method to study postprandial airway inflammation in older adults. Purpose: To investigate whether older individuals have greater postprandial airway inflammation compared to younger counterparts, and to explore whether exercise may modify the postprandial airway response in older adults. Methods: 12 younger adults (23.3±3.9 years; 5 M/7 F) and 12 older adults (67.7±6 …


The Effect Of Varying Fatty Acid Composition In A High-Fat Meal And Its Impact On Postprandial Airway Inflammation, Breanna L. Davidson May 2020

The Effect Of Varying Fatty Acid Composition In A High-Fat Meal And Its Impact On Postprandial Airway Inflammation, Breanna L. Davidson

Masters Theses, 2020-current

The Western Diet is typically high in saturated fats (SF) or omega-6 polyunsaturated fatty acids (O6FA) with insufficient amounts of omega-3 polyunsaturated fatty acids (O3FA). When chronic, this diet has been associated with an increased risk of respiratory diseases. PURPOSE: To examine the effect of varying the fatty acid composition of an acute High-Fat Meal (HFM) on postprandial airway inflammation. METHODS: Fifteen individuals [6 M, 9 F; body mass index (BMI) = 25.3 ± 6.6 kg/m2] consumed three HFM smoothies separated by at least 48 hours. The three smoothies were high in SF, O6FA, and O3FA …