Life Sciences Commons^™

Does Tssh Deletion In Paraburkholderia Bonniea Affect Its Symbiosis With Dictyostellum Discoideum?, Anna Chen

Honors Theses

Paraburkholderia are amoeba resistant, gram negative bacteria that form facultative symbiotic relationships with D. discoideum, a soil dwelling amoeba host. Three species of Paraburkholderia, P. agricolaris, P. hayleyella, and P. bonniea are able to persistently infect nonnative, or symbiont free, D. discoideum. These three species share a type III secretion system (T3SS) and type VI secretion system (T6SS) that is absent in other close relatives We hypothesized that the ability to persistently infect D. discoideum may be partially attributed to the T3SS and T6SS shared across the three species of Paraburkholderia.

The goal was to test the phenotypic effect of …

Microbiome Community And Parasitic Infections In Wild Bees, Mark G. Young

Honors Theses

The microbiome is increasingly recognized for its complex relationship with host fitness. Akin to primates and other social animals, bumblebees harbor a specific microbiome derived from social contact. The bumblebee microbiome is characteristically species poor, with just a few “core” phylotypes accounting for the majority of total abundance. Genomic analyses reveal phylogenetic congruence and adaptation of the core endosymbionts to the bumblebee gut, indicating a shared evolutionary history. Prior investigations reveal that the relative abundance of core microbes is negatively associated with infection by a trypanosome, Crithidia bombi, and that the microbiome has a mechanistic role in immunity. As …