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Articles 1 - 6 of 6
Full-Text Articles in Life Sciences
Assessing Genetic Differentiation Among Populations Of The Invasive Plant Impatiens Glandulifera In Maine, Jordan R. Schoonover
Assessing Genetic Differentiation Among Populations Of The Invasive Plant Impatiens Glandulifera In Maine, Jordan R. Schoonover
Honors Theses
The annual herbaceous plant Impatiens glandulifera Royle is native to the Himalayas and is a significant invasive species in Europe. In the past century, it was introduced to the United States, where it has become established in 12 states. This study evaluated genetic differentiation among four Maine populations, to address a theory that posits hybridization of distinct lineages as a trigger for invasiveness. Regions of microsatellite repeats were evaluated at two polymorphic loci for 41 plants sampled from the four populations. A striking finding was that the observed heterozygosity was substantially higher than the heterozygosity expected from random combination of …
The Differential Roles Of D-Pax2 Variants In Regulating Drosophila Eye And Bristle Development, Colin J. O’Shea
The Differential Roles Of D-Pax2 Variants In Regulating Drosophila Eye And Bristle Development, Colin J. O’Shea
Honors Theses
The ability to appropriately interact with the environment is crucial to an organism’s survival. The establishment of functional sensory systems, such as the bristles and eyes in Drosophila, is a critical event during the development of the organism. The transcription factor D Pax2 is involved in the differentiation of the shaft and glial cells in the developing bristle (Kavaler et al., Dev, 126:2261-2272, 1999) and of the cone and primary pigment cells in the developing eye (Fu and Noll, Genes Dev, 11:389-405, 1997). How D-Pax2 contributes to distinct differentiative pathways in different cell types is not known. Recent work by …
The Role Of Taabf1 In Abscisic Acid-Mediated Suppression Of 𝒶-Amylase Gene Expression In Cereal Grains, Lauren J. Harris
The Role Of Taabf1 In Abscisic Acid-Mediated Suppression Of 𝒶-Amylase Gene Expression In Cereal Grains, Lauren J. Harris
Honors Theses
The phytohormones gibberellin (GA) and abscisic acid (ABA) regulate important developments events in germinating seeds. Specifically, GA induces the expression of hyrolase genes, like the α-amylase gene Amy32b, which mobilizes starch reserves to be used by the embryo, and ABA suppresses this induction. Recent advancements identified ABA and GA receptors and key components in the signaling pathways, however, the mechanism of crosstalk between the hormones remains largely unknown. To further elucidate the mechanism of ABA suppression of GA-induced genes, we focused on the transcription factor TaABF1, a member of the ABA response element binding factor family. TaABF1 has been shown …
The Wheat Bzip Factor, Taabf1, Mediates Aba-Induced Gene Expression In Bombarded Barley Aleurone Layers, Benjamin R. Keyser
The Wheat Bzip Factor, Taabf1, Mediates Aba-Induced Gene Expression In Bombarded Barley Aleurone Layers, Benjamin R. Keyser
Honors Theses
The plant hormone Abscisic acid (ABA) plays a central role in maturation and germination in seeds, as well as mediating adaptive responses to abiotic environmental stresses. ABA induces the expression of many genes, including late-embryogenesis-abundant genes such as HVA1. To elucidate the ABA signaling pathway leading to HVA1 expression, we focus on the bZIP factor TaABF1. Analysis of the interplay between ABA and TaABF1 in the aleurone cells of imbibing cereal grains indicated that the two are not additive in their induction of the HVA1 promoter. A synthetic ABA analog, PBI-51, did not specifically inhibit the effect of exogenous ABA …
Patterns Of Apoptotic Poly(Adp-Ribose) Polymerase Cleavage Induced By Laromustine And Its Analogs, Adam N. Paine
Patterns Of Apoptotic Poly(Adp-Ribose) Polymerase Cleavage Induced By Laromustine And Its Analogs, Adam N. Paine
Honors Theses
The anticancer prodrug Laromustine (VNP40101M) has produced promising remission rates in clinical trials among leukemic patients relative to currently available chemotherapeutics. Such improvements demand that the agent’s mechanism of action be elucidated. This study aimed to determine the role of poly(ADP-ribose) polymerase (PARP) in Laromustine-induced cell death. Previous studies indicated that the methyl isocyanate produced upon activation of Laromustine is largely responsible for its effective induction of apoptosis. Results reported herein strongly support the activation of a PARP-dependent apoptotic pathway by Laromustine’s carbamoylating and chlorethylating subspecies. Furthermore, it is evident that the Laromustine-induced PARP-dependent apoptosis is primarily attributable to methyl …
Family Ties: Mainstream Environmentalists' Understanding Of Radical Environmentalism In America, Zachary W. Ezor
Family Ties: Mainstream Environmentalists' Understanding Of Radical Environmentalism In America, Zachary W. Ezor
Honors Theses
Environmentalism in the United States manifests itself in numerous ways. While American environmentalists have been grouped into broad camps over the years, observers have struggled to accurately classify the different components of the movement. Lately, environmentalists have been characterized based on their chosen modus operandi. Environmentalists who employ typical interest group tactics of policy advocacy and accept the notion of political compromise can generally be called 'mainstream.' Alternatively, those environmentalists who employ non-conventional strategies like direct action and take a no-compromise stance on environmental issues are typically described as 'radical.' Despite these distinctions, both radical and mainstream environmentalists are parts …