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Changsha University of Science and Technology
Agaricus Blazei Murill; polysaccharide; effervescent tablets; disintegration time
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Full-Text Articles in Life Sciences
Optimization On Formulation Of Agaricus Blazei Murill Polysaccharide Effervescent Tablets By Response Surface Methodology, Zhao Xiaotong, Zhang Yanqing, Li Chengbo, Zhang Huan
Optimization On Formulation Of Agaricus Blazei Murill Polysaccharide Effervescent Tablets By Response Surface Methodology, Zhao Xiaotong, Zhang Yanqing, Li Chengbo, Zhang Huan
Food and Machinery
In this study, the formulation of Agaricus Blazei Murill polysaccharide effervescent tablets were optimized. The normalized values (Z) of effervescent tablets of disintegration time and friability was selected as the response value. The influence factors for formulation of Agaricus Blazei Murill polysaccharide effervescent tablets were acid and alkali mass ratio, Citric acid mass fraction, PEG6000 mass fraction. Moreover, a three-variable, five-level code experiment was designed to optimize the formulation of Agaricus Blazei Murill polysaccharide effervescent tablets. The quadratic polynomial regression equation was built and could well describe the relationship between the dependent and independent variables. The optimal formulation was as …