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Full-Text Articles in Life Sciences
Red Blood Cell Aggregation Parameters Measured By Capillary Tube Aggregometer Using Venous And Capillary Blood Samples, Michael Simmonds, R. Christy, Sonya Marshall-Gradisnik, Herbert Meiselman, Oguz Baskurt
Red Blood Cell Aggregation Parameters Measured By Capillary Tube Aggregometer Using Venous And Capillary Blood Samples, Michael Simmonds, R. Christy, Sonya Marshall-Gradisnik, Herbert Meiselman, Oguz Baskurt
Sonya Marshall-Gradisnik
The extent of red blood cell (RBC) aggregation has widely been accepted as a reliable indicator of inflammatory processes. The ability to measure RBC aggregation indexes in capillary blood samples may simplify the application of the test and may bring advantages in its clinical usage as well as application in field studies. This study compared RBC aggregation indexes measured in venous and capillary blood samples using a newly developed capillary tube aggregometer. Although strong correlations between agreegation indexes measured in capillary and venous samples were detected, the indexes measure in venous samples were higher compared to capillary samples, thus indicating …
Assessment Of The Hemorheological Profile Of Koala And Echidna, Oguz Baskurt, Sonya Marshall-Gradisnik, Michael Pyne, Michael Simmonds, Ekua Brenu, Rhys Christy, Herbert Meiselman
Assessment Of The Hemorheological Profile Of Koala And Echidna, Oguz Baskurt, Sonya Marshall-Gradisnik, Michael Pyne, Michael Simmonds, Ekua Brenu, Rhys Christy, Herbert Meiselman
Sonya Marshall-Gradisnik
Koala, a marsupial, and echidna, a monotreme, are mammals native to Australia. Blood viscosity (62.5-1250 s-1), red blood cell (RBC) deformability, RBC aggregation, aggregability and surface charge, and hematological parameters were measured in blood samples from six koalas and six echidnas and compared to adult human blood. Koala had the largest RBC mean cell volume (107.7±2.6 fl) compared to echidna (81.3±2.6 fl) and humans (88.4±1.2 fl). Echidna blood exhibited the highest viscosity over the entire range of shear rates. Echidna RBC were significantly less deformable than koala RBC but more deformable than human RBC. Echidna RBC had significantly lower aggregability …
Haemorheology Of The Eastern Grey Kangaroo And The Tasmanian Devil, Michael Simmonds, Oguz Baskurt, Herbert Meiselman, Michael Pyne, Michael Kakanis, Ekua Brenu, James Keane, Rhys Christy, Sonya Marshall-Gradisnik
Haemorheology Of The Eastern Grey Kangaroo And The Tasmanian Devil, Michael Simmonds, Oguz Baskurt, Herbert Meiselman, Michael Pyne, Michael Kakanis, Ekua Brenu, James Keane, Rhys Christy, Sonya Marshall-Gradisnik
Sonya Marshall-Gradisnik
The blood of two Australian marsupials, the eastern grey kangaroo (Macropus giganteus) and the Tasmanian devil (Sarcophilus harrisii), has been reported to have greater oxygen-carrying capacity (i.e. haemoglobin content) when compared with that of placental mammals. We investigated whether alterations of blood rheological properties are associated with the increased oxygen-carrying capacity of these marsupials. Eastern grey kangaroos (n = 6) and Tasmanian devils (n = 4) were anaesthetised for blood sampling; human blood (n = 6) was also sampled for comparison. Laboratory measurements included blood and plasma viscosity, red blood cell (RBC) deformability, RBC aggregation and the intrinsic tendency of …
Erythrocyte Aggregation And Neutrophil Function In An Aging Population, Rhys Christy, Oguz Baskurt, Gregory Gass, A. Gray, Sonya Marshall-Gradisnik
Erythrocyte Aggregation And Neutrophil Function In An Aging Population, Rhys Christy, Oguz Baskurt, Gregory Gass, A. Gray, Sonya Marshall-Gradisnik
Sonya Marshall-Gradisnik
There are limited investigations which have examined the relationship between neutrophil activation and erythrocyte aggregation in older persons. The purpose of the present study was to investigate the relationship between neutrophil activation and erythrocyte aggregation (EA) in an aging population. Twenty-eight male and female subjects were allocated into one of four groups with 7 participants in each group (group 1, 20–29 years; group 2, 30–39 years; group 3, 40–49 years; group 4, 50–59 years). EA was determined using the Myrenne aggregometer. Neutrophil function (respiratory burst and phagocytic activity) was assessed using flow cytometry. EA was found to increase with age. …