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Antimicrobial

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Investigation Of Antimicrobial Properties Of Rhus Ovata Extracts, Sydney T. Adams Mar 2018

Investigation Of Antimicrobial Properties Of Rhus Ovata Extracts, Sydney T. Adams

Seaver College Research And Scholarly Achievement Symposium

Native peoples of Southern California historically used a variety of local plants as remedies for illnesses. Chaparral species such as Rhus ovata (sugar bush) were widely available and were used to ease headaches, coughs and chest pains, and colds. In light of the historical importance of this plant and other chaparral species, recent fungal pathogen-induced diebacks of Malosma laurina, a species closely related to R. ovata, have raised questions regarding the innate defenses of these plants against fungal pathogens. We attempted to scientifically evaluate the traditional medicinal use of R. ovata and its antifungal resistance by testing two …

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The New Penicillin?, Nikki Huynh Apr 2017

The New Penicillin?, Nikki Huynh

Nikki Huynh

Clostridium difficile infects and kills 30,000-40,000 people a year in the United States. In order to target and minimize the spread of C. difficile we are screening puupehenone, a natural marine product that is excreted from some species of sponges and coral as a defense mechanism, and repurposing its role for medical use. Our research primarily focuses on determining puupehenone’s antimicrobial properties. This was determined by testing the minimum inhibitory concentration (MIC) of puupehenone as it relates to a single strain of C. difficile, and then observing whether the antimicrobial properties hold across multiple strains of the bacterium. The strain …

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