Life Sciences Commons^™

A Machine Learning Approach To Post-Market Surveillance Of Medical Devices, Jonathan Bates, Shu-Xia Li, Craig Parzynski, Ronald Coifman, Harlan Krumholz, Joseph Ross

Yale Day of Data

Post-market surveillance is a collection of processes and activities used by product manufacturers and regulators, such as the U.S. Food and Drug Administration (FDA) to monitor the safety and effectiveness of medical devices once they are available for use “on the market”. These activities are designed to generate information to identify poorly performing devices and other safety problems, accurately characterize real-world device performance and clinical outcomes, and facilitate the development of new devices, or new uses for existing devices. Typically, a device is monitored by comparing adverse events in the exposed population to a matched unexposed population. This research considers …

A Comparison Between Mri Findings And Post Operative Reports Of Labral Tears In The Shoulder, Breanna Davis

CLAS: Colby Liberal Arts Symposium

This experiment investigates the effectiveness of MR arthrography in 28 patients seen at Maine General Orthopedics over the last three years. All 28 patients had an arthroscopic surgery on the shoulders labrum by Dr. Anthony Mancini. I hypothesize the MR arthrography is accurate in diagnosing tears, but not accurate in describing the size and location of the tears. The results found portray the accuracy between MR arthrography findings and the post-operative reports. The study focuses not only on the ability of the MR arthrography to detect a labral tear, but also its effectiveness of finding the location (superior, posterior, inferior, …

Arboretum Pavilion, Jessica Lunde

CLAS: Colby Liberal Arts Symposium

Colbys Arboretum is one of the most aesthetically appealing parts of the campus as well as one of the best educational tools we have. However, it is, unfortunately, underutilized by students and by the public. Theres so much to learn from this environment in terms of scientific study of the environment, but also in terms of self-reflection. The arboretum has been described as a place where one can think without pressure and the structure is guided by this idea of escape.

Regeneration After Destruction: An Investigation About Deforestation For Fruit Boxes In The Provinces Of Tungurahua And Pastaza, Ecuador, Julia Rogers

CLAS: Colby Liberal Arts Symposium

The extraction of wood for use as boxes for fruit in the region between Baos and Puyo in the provinces of Tungurahua and Pastaza in Ecuador is a large source of deforestation in the area. The purpose of the study is to examine the effect of this deforestation on the insects, birds, and seedlings to better understand the effects of small scale deforestation in the cloud forest of Ecuador. Six different sites were studied; 2 sites were cut within 2014, 1 site in 2012, 1 site is a forest of 4 to 8 years, and 2 sites are mature forest. …

Demographic Survey Of The Sohisika (Schizolaena Tampoketsana), James Lucas

CLAS: Colby Liberal Arts Symposium

The sohisika (Schizolaena tampoketsana; family Sarcolaenaceae) is a little-known, highly threatened angiosperm endemic to the forest fragments and savanna of the Hauts Plateaux region at Ankafobe Commune, Madagascar. Through targeted surveillance of sohisika at Ankafobe, this study aimed primarily to characterize the demography of the sohisika via GPS mapping of latitude, longitude, and altitude, through dendrometric measures such as height and diameter at breast height (DBH), and through calculation of distribution patterns via Morisitas index. Secondary goals aimed to describe the ecology of the sohisika within its environment and hoped to identify patterns between age class, aspect, habitat, and surrounding …

Demonstration Of Adaptive Optics In A Laboratory Setting, Jianing Yang

CLAS: Colby Liberal Arts Symposium

We constructed a simple adaptive optics system to demonstrate how a laser guide star coupled with a deformable mirror and wavefront sensor can be used to correct for distortions caused by turbulence in the Earths atmosphere. Adaptive optics (AO) systems are currently implemented at a number of national astronomical observatories, including the W. M. Keck Observatory, Gemini, and Subaru, and is a key design component for the next generation of very large (30-meter-class) ground-based telescopes. Adaptive optics is crucial for improving spatial resolution of ground-based imaging in astronomy. Using AO, we are able to achieve better image quality with the …

The Effects Of Flooding On Photosynthesis, Transpiration, And Stomatal Conductance Of Three Bottomland Hardwood Species, Angela Sutherland, Hans Williams

Bright Ideas Conference

Many tree species are able to adapt to harsh environmental conditions in order to survive. The degree of adaptability can determine how long a species can survive during prolonged environmental stress. This experiment monitored the effects of flooding on the photosynthesis, transpiration, and stomatal conductance of three bottomland hardwood tree species: water oak (Quercus nigra), willow oak (Quercus phellos), and bald cypress (Taxodium distichum).

Is There A Relationship Between Physical Inactivity And Visceral Fat Accumulation In Pregnant Women?, Ashlyn R. Showalter, Danielle Brown

Symposium of Student Scholars

Association of Physical Inactivity with Visceral Fat Accumulation in Pregnant Women

Ashlyn Showalter, Danielle Brown

Introduction: Abdominal obesity is associated with chronic diseases such as obesity and coronary artery disease (1). Abdominal (or visceral) fat is strongly correlated with an inactive and sedentary lifestyle. Recent research shows that pregnancy is associated with high levels of visceral fat beyond appropriate levels; however, no studies have linked them with physical inactivity. Objective: The purpose of this study is to examine the relationship between physical inactivity and high visceral fat accumulation in pregnancy.

Methods:

•We recruited eleven pregnant women who are currently in …

How Does The Exploitation And Degradation Of Finite Natural Resources By Industrial Oil Producers Effect Our Future Planetary Environment?, Zachary J. King Mr.

Symposium of Student Scholars

Zachary King

Dr. Tu

26 March 2015

GEOG 3700

Abstract

The purpose of this presentation is to communicate content of the reports given by credible institution on the degradation and exploitation of finite natural resources by corporate institutions, for short term financial gain, and how it will effect the future planetary environment. Methods used in obtaining this research range from point source observation directly from oil spills in the Gulf or pipe leaks in the Mid-West, to analytical and numerical data quantifications gathered over a period of two decades. This presentation encompasses a wide scope of information concerning the way …

Repsa-Directed Identification Of Dna-Binding Specificity For Orphan Transcription Factors, Kamir Hiam

Symposium of Student Scholars

The function of many genes and the biological roles of their encoded products are still not well characterized. Given the sequence-specific DNA-binding properties of transcription factor proteins, it is possible to purify them, identify the responsible polypeptide(s), determine their consensus binding sequences, and identify their genomic binding sites. Thus, one can go from cellular extract to proposed biological regulatory roles in relatively short order. Our goal is to identify and characterize orphan DNA-binding proteins in the model organism E. coli K12 using the novel combinatorial technique, REPSA (Restriction Endonuclease Protection Selection Amplification), as well as further develop the REPSA to …