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Full-Text Articles in Life Sciences

A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi Sep 2012

A Link Between Chronic Sleep Restriction And Obesity: Methodological Considerations, Christopher Magee, Donald Iverson, Xu-Feng Huang, Peter Caputi

Xu-Feng Huang

Emerging evidence suggests that chronicsleeprestriction contributes to obesity. Targeting short sleep duration may therefore offer a novel and effective method of preventing and treating obesity. However, this area of research is only in its infancy, and a complete understanding of how chronicsleeprestriction and obesity are linked is currently lacking. The aim of this paper is to briefly review epidemiological evidence for an association between chronicsleeprestriction and obesity in adults, and outline the key methodological limitations of these studies. Particular attention is paid to the methods used to measure sleep and obesity, as well as the need to control for potential …


Dietary Fat And Carbohydrate Composition: Metabolic Disease, Marc Brown, Len Storlien, Xu-Feng Huang, Linda Tapsell, Paul Else, Janine Higgins, Ian Brown Sep 2012

Dietary Fat And Carbohydrate Composition: Metabolic Disease, Marc Brown, Len Storlien, Xu-Feng Huang, Linda Tapsell, Paul Else, Janine Higgins, Ian Brown

Xu-Feng Huang

No abstract provided.


Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer Sep 2012

Effects Of Diets High In Whey, Soy, Red Meat And Milk Protein On Body Weight Maintenance In Diet-Induced Obesity In Mice, Xu-Feng Huang, Y Liu, Gita Rahardjo, Peter Mclennan, Linda Tapsell, William Buttemer

Xu-Feng Huang

This study examined the effects of different food sources of protein on energy intake, body weight maintenance, and on the responses of plasma leptin, insulin and adiponectin in chronic high-fat diet-induced obese mice. Obesity was induced in 47 mice with a high-fat diet for 20 weeks. They were divided into five diet groups to test the effects of a higher protein proportion (30% energy), achieved at the expense of carbohydrate. For the next eight weeks, four of the groups were fed diets of chow formulated with whey, soy, red meat or milk while the control group continued on their high-fat …


Relationships Between Clinical Data And Baseline Eating Behaviours In A Sample Of Overweight Volunteers For A Dietary Intervention Trial, Lynette Mackey De Paiva, Lynda Gillen, Linda Tapsell, Marijka Batterham, Xu-Feng Huang, Rachel Cavanagh, Meredith Kennedy Sep 2012

Relationships Between Clinical Data And Baseline Eating Behaviours In A Sample Of Overweight Volunteers For A Dietary Intervention Trial, Lynette Mackey De Paiva, Lynda Gillen, Linda Tapsell, Marijka Batterham, Xu-Feng Huang, Rachel Cavanagh, Meredith Kennedy

Xu-Feng Huang

No abstract provided.


Dietary And Clinical Risk Profiles Of A Sample Of Healthy Overweight Adults Provide Targets For Dietary Advice In An Intervention Trial, Lynda Gillen, Linda Tapsell, Marijka Batterham, Xu-Feng Huang, Rachel Cavanagh, Meredith Kennedy Sep 2012

Dietary And Clinical Risk Profiles Of A Sample Of Healthy Overweight Adults Provide Targets For Dietary Advice In An Intervention Trial, Lynda Gillen, Linda Tapsell, Marijka Batterham, Xu-Feng Huang, Rachel Cavanagh, Meredith Kennedy

Xu-Feng Huang

No abstract provided.


An Investigation Of The Dimensionality Of The Pittsburgh Sleep Quality Index In Australian Adults, Christopher Magee, Peter Caputi, Donald Iverson, Xu-Feng Huang Sep 2012

An Investigation Of The Dimensionality Of The Pittsburgh Sleep Quality Index In Australian Adults, Christopher Magee, Peter Caputi, Donald Iverson, Xu-Feng Huang

Xu-Feng Huang

The Pittsburgh Sleep Quality Index (PSQI) is widely used to assess subjective sleep quality in clinical and non-clinical settings. Although the PSQI is routinely scored to provide a single sleep quality factor, two recent studies suggest that multiple factor scoring methods could be more appropriate. As a consequence, the present study investigated for the dimensionality and factor structure of the PSQI in 364 Australian adults aged 18 to 59 years. The results demonstrate that two factor and three factor scoring models were favored statistically over the single factor model. These results add to recent findings and suggest that scoring the …


Alterations To Melanocortinergic, Gabaergic And Cannabinoid Neurotransmission Associated With Olanzapine-Induced Weight Gain, Katrina Weston-Green, Xu-Feng Huang, Chao Deng Sep 2012

Alterations To Melanocortinergic, Gabaergic And Cannabinoid Neurotransmission Associated With Olanzapine-Induced Weight Gain, Katrina Weston-Green, Xu-Feng Huang, Chao Deng

Xu-Feng Huang

Background/Aim: Second generation antipsychotics (SGAs) are used to treat schizophrenia but can cause serious metabolic side-effects, such as obesity and diabetes. This study examined the effects of low to high doses of olanzapine on appetite/ metabolic regulatory signals in the hypothalamus and brainstem to elucidate the mechanisms underlying olanzapineinduced obesity. Methodology/Results: Levels of pro-opiomelanocortin (POMC), neuropeptide Y (NPY) and glutamic acid decarboxylase (GAD65, enzyme for GABA synthesis) mRNA expression, and cannabinoid CB1 receptor (CB1R) binding density (using [3H]SR- 141716A) were examined in the arcuate nucleus (Arc) and dorsal vagal complex (DVC) of female Sprague Dawley rats following 0.25, 0.5, 1.0 …


Does Hero Always Help? Differences In Nutrient Intake Among Obese Subjects With And Without Type 2 Diabetes Mellitus Prior To Dietary Intervention, Sze Yen Tan, Lynda Gillen, Marijka Batterham, Xu-Feng Huang, Cassandra Quick, Yasmine Probst, Serina Faraji, Linda Tapsell Sep 2012

Does Hero Always Help? Differences In Nutrient Intake Among Obese Subjects With And Without Type 2 Diabetes Mellitus Prior To Dietary Intervention, Sze Yen Tan, Lynda Gillen, Marijka Batterham, Xu-Feng Huang, Cassandra Quick, Yasmine Probst, Serina Faraji, Linda Tapsell

Xu-Feng Huang

No abstract provided.


Transmembrane Domain Nrg1 Mutant Mice Show Altered Susceptibility To The Neurobehavioural Actions Of Repeated Thc Exposure In Adolescence, Leonora Long, Rose Chesworth, Xu-Feng Huang, Iain Mcgregor, Jonathon Arnold, Tim Karl Sep 2012

Transmembrane Domain Nrg1 Mutant Mice Show Altered Susceptibility To The Neurobehavioural Actions Of Repeated Thc Exposure In Adolescence, Leonora Long, Rose Chesworth, Xu-Feng Huang, Iain Mcgregor, Jonathon Arnold, Tim Karl

Xu-Feng Huang

Heavy cannabis abuse increases the risk of developing schizophrenia. Adolescents appear particularly vulnerable to the development of psychosis-like symptoms after cannabis use. To test whether the schizophrenia candidate gene neuregulin 1 (NRG1) modulates the effects of cannabinoids in adolescence, we tested male adolescent heterozygous transmembrane domain Nrg1 mutant (Nrg1 TM HET) mice and wild type-like littermates (WT) for their neurobehavioural response to repeated Δ9-tetrahydrocannabinol (THC, 10 mg/kg i.p. for 21 d starting on post-natal day 31). During treatment and 48 h after treatment withdrawal, we assessed several behavioural parameters relevant to schizophrenia. After behavioural testing we measured autoradiographic …