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Articles 1 - 9 of 9
Full-Text Articles in Life Sciences
Impact Of Fish Oil On Intestinal Permeability, Inflammation, And Performance In Swine, Anthony Fernando Alberto
Impact Of Fish Oil On Intestinal Permeability, Inflammation, And Performance In Swine, Anthony Fernando Alberto
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Our research examined the effects of fish oil supplementation on intestinal permeability, systemic inflammation and performance in piglets. An lipopolysaccharide (LPS) challenge was done to stimulate the synthesis and release of the cytokines, in an effort to mimic the immune response that piglets would have when facing stress or pathogen challenge. Fish oil increased feed intake but did not affect growth when compared to control. Total fatty acid digestibility increased by 6% when fish oil was included in the diet. Also, we observed a 16% increase on 16-carbon fatty acids digestibility. Fish oil did not affect the plasma …
Cranial Cruciate Ligament Desmotomies In Sheep Resulting In Peroneus Tertius Injury, Peter J. Welsh, Crystal G. Collier, Holly M. Clement, Michael N. Vakula, Jeffrey B. Mason
Cranial Cruciate Ligament Desmotomies In Sheep Resulting In Peroneus Tertius Injury, Peter J. Welsh, Crystal G. Collier, Holly M. Clement, Michael N. Vakula, Jeffrey B. Mason
Animal, Dairy, and Veterinary Science Student Research
Surgical destabilization of the stifle joint via cranial cruciate ligament desmotomy (CCLD) is a routine procedure for the study of osteoarthritis (OA). Traditionally performed in rats, rabbits, cats, and dogs, CCLD in sheep provides an opportunity to study the pathology and treatment of joint instability in a species whose stifle better represents the equivalent human femorotibial joint. The surgical approaches for CCLD in sheep are variable and can result in inconsistent outcomes. Eight sheep underwent CCLD for use in a gene therapy study. We report this case in which six of the eight sheep were clinically diagnosed by pathognomonic signs …
The Effects Of Trace Mineral Supplementation On Performance, Health, And Carcass Quality Of At-Risk Mineral Deficient Feedlot Cattle, Tevan J. Brady
The Effects Of Trace Mineral Supplementation On Performance, Health, And Carcass Quality Of At-Risk Mineral Deficient Feedlot Cattle, Tevan J. Brady
All Graduate Theses and Dissertations, Spring 1920 to Summer 2023
Morbidity in feedlot cattle due to disease is a common economical loss for feedlot producers. Utah is not typically considered a ‘feedlot state’, but there are several producers in the southern part of the state that specialize in receiving at-risk cattle. These cattle are at-risk because they are coming from areas known to be mineral deficient. Areas such as the western US, are known to be deficient in several trace minerals important in immune response. Therefore, it is critical that producers have an adequate plan to decrease the negative effects that this has on economic viability of their beef operations, …
Using Handmade Cloning To Reduce Oocyte Mitochondria In Reconstructed Embryos, Laura Adams
Using Handmade Cloning To Reduce Oocyte Mitochondria In Reconstructed Embryos, Laura Adams
Student Research Symposium
Mitochondrial heteroplasmy, the presence of more than one population of mitochondrial DNA (mtDNA) in one cell, can cause metabolic issues and reduced ATP synthesis, even at relatively low levels. The presence of this condition in somatic cell nuclear transfer (SCNT) embryos likely contributes to reduced prenatal and postnatal viability: the majority of the oocyte’s mitochondria is still present at the time of nuclear transfer, as well as through any further embryonic development post-fusion and activation. Though the somatic cell also contributes its mitochondria (which can successfully communicate with its nucleus), the oocyte’s mitochondria compose a greater proportion of the total …
Detecting Dna Oxidation In Sperm, Alexie Zwerdling
Detecting Dna Oxidation In Sperm, Alexie Zwerdling
Student Research Symposium
Declining body-wide levels of nicotinamide adenine dinucleotide (NAD) that are present in normal aging men are linked to decreased sperm quality and DNA integrity. When NAD is low, the amount of oxidative stress on the DNA appears to be increased, due to the limited regeneration of the antioxidant glutathione, which is NAD-dependent. We therefore hypothesize that the increased sperm DNA damage in the aging male is caused by an elevated formation of 8-oxoguanine in the DNA, caused by increased oxidative stress when NAD levels are low. To test this hypothesis, a transgenic mouse model (ANDY mouse) was used to create …
Roles Of Nad+ In Testicular Aging And Epigenetic Sperm Modifications, Renata Hoskova
Roles Of Nad+ In Testicular Aging And Epigenetic Sperm Modifications, Renata Hoskova
Student Research Symposium
Since 1980, the average age of first-time fathers has been increasing. With increased age, sperm chromatin quality and nicotinamide adenine dinucleotide (NAD) levels are reduced. In order to condense around protamines, sperm DNA undergoes breaks, at which time epigenetic reprogramming occurs. In humans, about 2% of DNA stays wound to histones in spermatozoa. Histones carry post-translational modifications that control gene activity and have the potential to transmit epigenetic information to the offspring. Analysis of epigenetic sperm modifications is being conducted within niacin deficient versus niacin replete mice. The experimental plan includes the characterization of histone exchange in elongating spermatids via …
Fecal Microbiota Transfer (Fmt) From Tumor-Bearing Mice Fed The Total Western Diet (Twd) Does Not Contribute To A Higher Tumor Burden In Mice Fed A Healthy Diet, Porter Green
Student Research Symposium
Colorectal cancer (CRC) is the third most common cause of cancer death in the United States. Diet and gut microbiome have shown to influence the development of colitis associated colorectal cancer (CAC). For this study, the goal was to determine the association between colon inflammation, diet and microbiome in the development of CAC in mice. The primary objective of this study was to determine the contribution of gut microbiota from mice donors who have previously consumed one of two basal diets: 1) the standard AIN93G diet, which is designed to promote rodent health; and 2) the total Western diet (TWD), …
Bolstering Southeast Asia's Livestock Biosecurity And Climate Change Resilience Essential For Global Health, Madelyn Kunzler
Bolstering Southeast Asia's Livestock Biosecurity And Climate Change Resilience Essential For Global Health, Madelyn Kunzler
Student Research Symposium
A large factor of climate change is its effect on infectious zoonotic diseases. Zoonotic diseases are diseases that can be transferred from animals into humans. Cases of zoonotic diseases have increased as humans have interacted more with animals, and as worldwide travel has become more frequent. It is predicted that 60% of emerging human diseases will be zoonotic. The cases will continue to increase to due climate change. As climate change continues, research has shown that new diseases will emerge from the melting permafrost and ice caps. It is also likely that pre-existing diseases will be able to migrate to …
Roles Of Nad In Dna Repair And Response To Oxidative Stress, Micah Forbush
Roles Of Nad In Dna Repair And Response To Oxidative Stress, Micah Forbush
Student Research Symposium
It has become a common trend for people to start their families at a later age, often due to lifestyle choices like achieving career goals first and waiting to achieve financial stability. Along with this trend of increasing parental age comes another, the decrease in fertility. While it is well established that female fertility declines significantly with age, current research is showing that male fertility may be impacted just as much. NAD (Nicotinamide Adenine Dinucleotide) is an important biochemical cofactor in most metabolic reactions, and importantly, is it also essential for DNA repair. As age increases in humans, the amount …