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Full-Text Articles in Life Sciences
Dihydrodinophysistoxin-1 Produced By Dinophysis Norvegica In The Gulf Of Maine, Usa And Its Accumulation In Shellfish, Jonathan R. Deeds, Whitney L. Stutts, Mary Dawn Celiz, Jill Macleod, Amy E. Hamilton, Bryant J. Lewis, David W. Miller, Kohl Kanwit, Juliette L. Smith, Et Al
Dihydrodinophysistoxin-1 Produced By Dinophysis Norvegica In The Gulf Of Maine, Usa And Its Accumulation In Shellfish, Jonathan R. Deeds, Whitney L. Stutts, Mary Dawn Celiz, Jill Macleod, Amy E. Hamilton, Bryant J. Lewis, David W. Miller, Kohl Kanwit, Juliette L. Smith, Et Al
VIMS Articles
Dihydrodinophysistoxin-1 (dihydro-DTX1, (M-H)−m/z 819.5), described previously from a marine sponge but never identified as to its biological source or described in shellfish, was detected in multiple species of commercial shellfish collected from the central coast of the Gulf of Maine, USA in 2016 and in 2018 during blooms of the dinoflagellate Dinophysis norvegica. Toxin screening by protein phosphatase inhibition (PPIA) first detected the presence of diarrhetic shellfish poisoning-like bioactivity; however, confirmatory analysis using liquid chromatography-tandem mass spectrometry (LC-MS/MS) failed to detect okadaic acid (OA, (M-H)−m/z 803.5), dinophysistoxin-1 (DTX1, (M-H)−m/z 817.5), or dinophysistoxin-2 (DTX2, (M-H) …