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Alcohol Use Disorders And An Fmri Stress Task: A Connectivity Analysis, Natasha E. Wright
Alcohol Use Disorders And An Fmri Stress Task: A Connectivity Analysis, Natasha E. Wright
Theses and Dissertations
Little research has been conducted on neuronal stress processing in individuals
with alcohol dependence (AD). The present study examined neural stress response in AD individuals compared to controls using an fMRI stress task, assessing amygdala
activation and its connectivity to the medial prefrontal cortex (mPFC). Further, the study
analyzed the impact of hormone levels and subjective stress on frontal-limbic
connectivity patterns.
Ten abstinent AD individuals and 11 controls were recruited. Subjects
participated in an fMRI stress task. A region of interest (amygdala) analysis was
conducted using area-under-the-curve. This activation was then examined in a whole brain functional connectivity analysis. Follow-up …