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Full-Text Articles in Life Sciences
Factors Influencing Primate Hair Microbiome Diversity, Catherine Kitrinos
Factors Influencing Primate Hair Microbiome Diversity, Catherine Kitrinos
Masters Theses
Primate hair is both a substrate upon which essential social interactions occur and an important host-pathogen interface. As commensal microbes provide important immune functions for their hosts, understanding the microbial diversity in primate hair could provide insight into primate immunity and disease transmission. While studies of human hair and skin microbiomes show differences in microbial communities across body regions, little is known about the nonhuman primate hair microbiome. In this study, we collected hair samples (n=159) from 8 body regions across 12 nonhuman primate species housed at 3 US institutions to examine 1) the diversity and composition of the primate …
De-Coding The Impact Of Evolved Changes In Gene Expression And Cellular Phenotype On Primate Evolution, Trisha Zintel
De-Coding The Impact Of Evolved Changes In Gene Expression And Cellular Phenotype On Primate Evolution, Trisha Zintel
Doctoral Dissertations
The goal of the dissertation work outlined here was to investigate the influence of proximal processes contributing to evolutionary differences in phenotypes among primate species. There are numerous previous comparative analyses of gene expression between primate brain regions. However, primate brain tissue samples are relatively rare, and my results have contributed to the pre-existing data on more well-studied primates (i.e. humans, chimpanzees, macaques, marmosets) as well as produced information on more rarely-studied primates (i.e. patas monkey, siamang, spider monkey). Additionally, the primary visual cortex has not previously been as extensively studied at the level of gene expression as other brain …
Loss Of Cell Surface Agal During Catarrhine Evolution: Possible Implications For The Evolution Of Resistance To Viral Infections And For Oligocene Lineage Divergence, Idalia Aracely Rodriguez
Loss Of Cell Surface Agal During Catarrhine Evolution: Possible Implications For The Evolution Of Resistance To Viral Infections And For Oligocene Lineage Divergence, Idalia Aracely Rodriguez
Doctoral Dissertations
The divergence of the two superfamilies belonging to the Infraorder Catarrhini –Cercopithecoidea (Old World monkeys) and Hominoidea (apes, including humans) – is generally assumed to have occurred during the Oligocene, between 38 and 20 million years ago. Genetic studies indicate that this time period was one of active genetic evolution under strong purifying selection for catarrhine primates. This includes selective pressures on the glycoprotein galactosyltransferase 1 (GGTA1) gene and subsequent inactivation “clocked” at approximately 28 ma, possibly prior to the Cercopithecoidea/Hominoidea split. The GGTA1 gene codes for an a1,3 galactosyltransferase (GT) enzyme that synthesizes a terminal disaccharide, …