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Ventilator Induced Lung Injury, John A. Johnson Jr.
Ventilator Induced Lung Injury, John A. Johnson Jr.
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Severe physical-trauma can lead to the development of acute respiratory distress syndrome (ARDS). Currently, the only known treatment for ARDS is mechanical ventilation. However, if mechanical ventilation is applied inappropriately further injury and malfunction of the lungs may occur, and thus, causing a ventilator induced lung injury (VILI). VILI has several manifestations including volutrauma, atelectrauma, and biotrauma. These mechanisms often exacerbate one another adding further insult to the injury. The goal of this current study is to establish a stable control pig model of ARDS as a comparison for ventilatory strategies that will act in a more protective manner than …