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The Effects Of Exercise Pattern And Intensity On The Expression Of Flk-1 And Flt-1 Receptors In The Hippocampus And Cerebellum, Morgan E. Stevenson
The Effects Of Exercise Pattern And Intensity On The Expression Of Flk-1 And Flt-1 Receptors In The Hippocampus And Cerebellum, Morgan E. Stevenson
Theses and Dissertations
Aerobic exercise benefits the body and brain. In the brain, these benefits include neuroprotection and improved cognition. These exercise-induced changes are attributed in part to angiogenesis: the growth of new capillaries from preexisting vessels. One critical factor involved in the regulation of angiogenesis is VEGF and its receptors Flk-1 and Flt-1. Although exercise is generally found to be beneficial, there are wide variations in the exercise regimens used across experiments. This study standardized some of these variations. In this study, rats were either assigned to a voluntary wheel running or a forced wheel running exercise condition. Within each condition, animals …