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Full-Text Articles in Life Sciences

Combining Demographic And Genetic Factors To Assess Population Vulnerability In Stream Species, Erin Landguth, C. C. Muhlfeld, R. S. Waples, L. Jones, Winsor H. Lowe, Diane C. Whited, J. Lucotch, H. Neville, Gordon Luikart Sep 2014

Combining Demographic And Genetic Factors To Assess Population Vulnerability In Stream Species, Erin Landguth, C. C. Muhlfeld, R. S. Waples, L. Jones, Winsor H. Lowe, Diane C. Whited, J. Lucotch, H. Neville, Gordon Luikart

Biological Sciences Faculty Publications

Accelerating climate change and other cumulative stressors create an urgent need to understand the influence of environmental variation and landscape features on the connectivity and vulnerability of freshwater species. Here, we introduce a novel modeling framework for aquatic systems that integrates spatially explicit, individual-based, demographic and genetic (demogenetic) assessments with environmental variables. To show its potential utility, we simulated a hypothetical network of 19 migratory riverine populations (e.g., salmonids) using a riverscape connectivity and demogenetic model (CDFISH). We assessed how stream resistance to movement (a function of water temperature, fluvial distance, and physical barriers) might influence demogenetic connectivity, and hence, …


The Genomic Architecture Of Population Divergence Between Subspecies Of The European Rabbit, Miguel Carneiro, Frank W. Albert, Sandra Afonso, Ricardo J. Pereira, Hernan Burbano, Rita Campos, Jose Melo-Ferreira, Jose A. Blanco-Aguiar, Rafael Villafuerte, Michael W. Nachman, Jeffrey M. Good, Nuno Ferrand Aug 2014

The Genomic Architecture Of Population Divergence Between Subspecies Of The European Rabbit, Miguel Carneiro, Frank W. Albert, Sandra Afonso, Ricardo J. Pereira, Hernan Burbano, Rita Campos, Jose Melo-Ferreira, Jose A. Blanco-Aguiar, Rafael Villafuerte, Michael W. Nachman, Jeffrey M. Good, Nuno Ferrand

Biological Sciences Faculty Publications

The analysis of introgression of genomic regions between divergent populations provides an excellent opportunity to determine the genetic basis of reproductive isolation during the early stages of speciation. However, hybridization and subsequent gene flow must be relatively common in order to localize individual loci that resist introgression. In this study, we used next-generation sequencing to study genome-wide patterns of genetic differentiation between two hybridizing subspecies of rabbits (Oryctolagus cuniculus algirus and O. c. cuniculus) that are known to undergo high rates of gene exchange. Our primary objective was to identify specific genes or genomic regions that have resisted …


Ex Uno Plures: Clonal Reinforcement Drives Evolution Of A Simple Microbial Community, Margie A. Kinnersley, Jared Wenger, Evgueny Kroll, Julian Adams, Gavin Sherlock, Frank Rosenzweig Jun 2014

Ex Uno Plures: Clonal Reinforcement Drives Evolution Of A Simple Microbial Community, Margie A. Kinnersley, Jared Wenger, Evgueny Kroll, Julian Adams, Gavin Sherlock, Frank Rosenzweig

Biological Sciences Faculty Publications

A major goal of genetics is to define the relationship between phenotype and genotype, while a major goal of ecology is to identify the rules that govern community assembly. Achieving these goals by analyzing natural systems can be difficult, as selective pressures create dynamic fitness landscapes that vary in both space and time. Laboratory experimental evolution offers the benefit of controlling variables that shape fitness landscapes, helping to achieve both goals. We previously showed that a clonal population of E. coli experimentally evolved under continuous glucose limitation gives rise to a genetically diverse community consisting of one clone, CV103, that …