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Antibacterial Anthranilic Derivatives From Geijera Parviflora, Qing-Yao Shou, Linda Banbury, Alan Maccarone, Dane Renshaw, Htwe Mon, Stefani Griesser, Hans Griesser, Stephen Blanksby, Joshua Smith, Hans Wohlmuth
Antibacterial Anthranilic Derivatives From Geijera Parviflora, Qing-Yao Shou, Linda Banbury, Alan Maccarone, Dane Renshaw, Htwe Mon, Stefani Griesser, Hans Griesser, Stephen Blanksby, Joshua Smith, Hans Wohlmuth
Dr Hans Wohlmuth
Five anthranilic acid derivatives, a mixture I of three new compounds 11′-hexadecenoylanthranilic acid (1), 9′-hexadecenoylanthranilic acid (2), and 7′-hexadecenoylanthranilic acid (3), as well as a new compound 9,12,15-octadecatrienoylanthranilic acid (4) together with a new natural product, hexadecanoylanthranilic acid (5), were isolated from Geijera parviflora Lindl. (Rutaceae). Their structures were elucidated by extensive spectroscopic measurements, and the positions of the double bonds in compounds 1–3 of the mixture I were determined by tandem mass spectrometry employing ozone-induced dissociation. The mixture I and compound 5 showed good antibacterial activity against several Gram-positive strains.