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Full-Text Articles in Life Sciences
Search For Host Factors Involved In Attachment Of Agrobacterium Tumefaciens To Plants, Anna Petrovicheva
Search For Host Factors Involved In Attachment Of Agrobacterium Tumefaciens To Plants, Anna Petrovicheva
Dissertations, Theses, and Capstone Projects
Agrobacterium tumefaciens is able to infect a diverse array of plants and causes crown gall disease. Typically these bacteria attach to plant roots and transform the plant cells to induce tumors. The mechanism of this attachment in the infection process is not yet fully understood. Using wild type Arabidopsis thaliana, Columbia-0, and several Arabidopsis mutant lines as a binding target, we screened for A. thaliana mutants with altered adhesion.
The A. thaliana mutant lines were selected in The Arabidopsis Information Resource (TAIR) according to possible location of the resulting protein and similarity to known transformation mutants. Of these mutants …
Novel Systems For The Functional Characterization Of Genes Related To Paclitaxel Metabolism In Taxus Cell Cultures, Khamkeo Vongpaseuth
Novel Systems For The Functional Characterization Of Genes Related To Paclitaxel Metabolism In Taxus Cell Cultures, Khamkeo Vongpaseuth
Open Access Dissertations
Human society has benefited greatly from plant secondary metabolites, often utilizing a variety of compounds as dyes, food additives, and drugs. In particular, pharmaceutical development has benefited greatly from plant secondary metabolites. One example of this utility is paclitaxel, a highly substituted diterpene approved in the treatment of breast cancer, ovarian cancer, non-small cell lung cancer, and the AIDSrelated Kaposi’s sarcoma. Demand of paclitaxel is likely to increase, due to the current examination of paclitaxel in numerous clinical trials against a variety of other cancers.
Taxus cell culture represents a production source of paclitaxel to meet future demand. However, paclitaxel …