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Epigenetic History Of An Arabidopsis Trans-Silencer Locus And A Test For Relay Of Trans-Silencing Activity, Huaxia Qin, Albrecht G. Von Arnim
Epigenetic History Of An Arabidopsis Trans-Silencer Locus And A Test For Relay Of Trans-Silencing Activity, Huaxia Qin, Albrecht G. Von Arnim
Plant Sciences Publications and Other Works
Background
Meiotically heritable epimutations affecting transgene expression are not well understood, even and in particular in the plant model species, Arabidopsis thaliana. The Arabidopsis trans-silencer locus, C73, which encodes a fusion protein between the repressor of photomorphogenesis, COP1, and green fluorescent protein (GFP-COP1), heritably modifies the expression pattern and cop1-like cosuppression phenotypes of multiple GFP-COP1 target loci by transcriptional gene silencing.
Results
Here we describe three additional features of trans-silencing by the C73 locus. First, the silencing phenotype of C73 and of similar complex loci was acquired epigenetically over the course of no more than two plant …