Open Access. Powered by Scholars. Published by Universities.®
- Keyword
- File Type
Articles 1 - 2 of 2
Full-Text Articles in Life Sciences
Primordial Germ Cell-Like Cells Differentiated In Vitro From Skin-Derived Stem Cells, Katja Linher, Paul Dyce, Julang Li
Primordial Germ Cell-Like Cells Differentiated In Vitro From Skin-Derived Stem Cells, Katja Linher, Paul Dyce, Julang Li
Paul W. Dyce
Background We have previously demonstrated that stem cells isolated from fetal porcine skin have the potential to form oocyte-like cells (OLCs) in vitro. However, primordial germ cells (PGCs), which must also be specified during the stem cell differentiation to give rise to these putative oocytes at more advanced stages of culture, were not systematically characterized. The current study tested the hypothesis that a morphologically distinct population of cells derived from skin stem cells prior to OLC formation corresponds to putative PGCs, which differentiate further into more mature gametes.
Methodology/Principal Findings When induced to differentiate in an appropriate microenvironment, a subpopulation …
Somatic Stem Cells Of Non-Gonadal Tissues: Their Germline Potential, Paul Dyce, Katja Linher, Julang Li
Somatic Stem Cells Of Non-Gonadal Tissues: Their Germline Potential, Paul Dyce, Katja Linher, Julang Li
Paul W. Dyce
No abstract provided.