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Physical Sciences and Mathematics

Theses/Dissertations

2021

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Full-Text Articles in Life Sciences

The Phase Behavior Of Ubqln Proteins And Implications For Protein Quality Control, Yiran Yang Dec 2021

The Phase Behavior Of Ubqln Proteins And Implications For Protein Quality Control, Yiran Yang

Dissertations - ALL

The ubiquitin-proteasome system (UPS) and autophagy are essential pathways for maintaining protein quality control (PQC) in cells. Misfolded proteins and large aggregates are cleared by UPS and autophagy signaled by ubiquitin (Ub) or polyubiquitin (polyUb) chains. Shuttle proteins facilitate cargo transporting by interacting with both ubiquitin and degradation machineries. Previously, our lab discovered that the shuttle protein Ubiquilin-2 (UBQLN2) is recruited to stress granules in cells and undergoes liquid-liquid phase separation (LLPS) in vitro. LLPS is a biophysical process by which proteins separate themselves from the surrounding aqueous solution by forming protein-rich droplets. The overarching goals of this work are …

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Fine Scales, Broad Consequences: Drivers And Effects Of Microclimatic Variation In Great Smoky Mountains National Park, Jordan Rebecca Stark Dec 2021

Fine Scales, Broad Consequences: Drivers And Effects Of Microclimatic Variation In Great Smoky Mountains National Park, Jordan Rebecca Stark

Theses - ALL

Climate is highly variable at scales that are not captured by most weather and climate models due to local effects of topography and living systems. This variation in microclimate has been noted for many decades but has been difficult to incorporate into quantitative understanding of ecological systems and processes due to the large amount of data and complex models required to adequately describe fine-scale patterns across complex landscapes. In recent years, models of thermal microclimate variation have been developed using low-cost temperature sensors, but few of these models have been used to predict the effects of microclimatic variation on ecological …

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Direct Single Molecule Imaging Of Enhanced Diffusion For Enzymes And Enzyme-Conjugated Dna Origami, Mengqi Xu Dec 2021

Direct Single Molecule Imaging Of Enhanced Diffusion For Enzymes And Enzyme-Conjugated Dna Origami, Mengqi Xu

Dissertations - ALL

Enzymes have been shown to diffuse faster in the presence of their substrates. Recently, we revealed new insights into this process of enhanced diffusion using single-particle tracking (SPT) with total internal reflection fluorescence (TIRF) microscopy. We found that the mobility of individual enzymes was enhanced three-fold in the presence of the substrate, and the motion remained Brownian. We showed that the relative increase in diffusion is independent of the total enzyme concentrations; and the oligomerization state of enzymes did not change during the catalytic turnover. These experiments ruled out the possibility that the enhanced enzyme diffusion was caused by the …

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Joint Management Of Upland & Aquatic Habitat For The California Red-Legged Frog & California Tiger Salamander, Kyle E. Verblaauw Dec 2021

Joint Management Of Upland & Aquatic Habitat For The California Red-Legged Frog & California Tiger Salamander, Kyle E. Verblaauw

Master's Projects and Capstones

As federally and state protected amphibians, the California tiger salamander (Ambystoma californiense) and the California red-legged frog (Rana draytonii) are recipients of ample management focus. Both species face a variety of threats, including habitat loss and alteration, introduction of non-native species, spread of disease, and effects of climate change. While management plans for the California tiger salamander and California red-legged frog exist, they frequently do not consider both species in tandem and often contain multiple shortcomings. This document aims to address the shortfalls of current management by providing practical recommendations for jointly managing the upland and …

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Computational Methods For Analysis Of Data For Conformational And Phase Equilibria Of Disordered Proteins, Jared Michael M Lalmansingh Dec 2021

Computational Methods For Analysis Of Data For Conformational And Phase Equilibria Of Disordered Proteins, Jared Michael M Lalmansingh

Arts & Sciences Electronic Theses and Dissertations

Intrinsically disordered proteins and regions (IDPs / IDRs) are a class of proteins with diverse conformational heterogeneity that do not fold into a tertiary structure due to the lack of a native structural state. Consequently, disordered proteins are remarkably flexible and exhibit multivalent properties that enable them to adopt myriad functional roles within the cell such as: signaling transduction, transcription, enzymatic catalysis, translation, and many more. Due to their multivalency, some IDPs undergo monomeric and heterotypic interactions which can drive phase separation. Such IDPs can form membraneless organelles with specific regulatory roles within the cell which include, but are not …

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Antimicrobial Activity Of Bacterial Virus Components: An Empirical Investigation Of The Killing Capacity Of Toxins From Burkholderia, Kyle Walny Dec 2021

Antimicrobial Activity Of Bacterial Virus Components: An Empirical Investigation Of The Killing Capacity Of Toxins From Burkholderia, Kyle Walny

Honors Projects

Given the growing issue in healthcare of antibiotic resistance, effective and safe alternative treatment methods are required. One of these possible alternative treatment methods is bacteriotoxins including bacteriocins and tailocins. The focus of this study is a bacteriotoxin from Burkholderia cenocepacia (ATCC 25608), which was induced for toxin using a modified UV light induction procedure and tested against a variety of Pseudomonas and Burkholderia for its killing capacity. Various other pathogenic strains were then induced with UV light and tested. The results showed that the toxin from ATCC 25608 was very effective against most of the Burkholderia tested and warrants …

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How Can Stem Retention Rates At Bgsu Be Increased Both In And Out Of The Classroom?, Josalyn A. Coffee Dec 2021

How Can Stem Retention Rates At Bgsu Be Increased Both In And Out Of The Classroom?, Josalyn A. Coffee

Honors Projects

Previous research in STEM student retention rates showed a gap in knowledge regarding why this group of student experience higher rates of burnout than other groups of students. This study investigated the barriers STEM students at BGSU experienced. A survey was sent out to STEM and non-STEM students alike that asked questions regarding student’s personal history before attending BGSU, their course experiences at BGSU, and the levels of support they have outside of BGSU. The survey data showed that there was little difference in the rates that students switch majors solely based on being in the STEM field. The data …

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Seasonal Flammability Comparisons Of Native And Exotic Plants In The Post Oak Savannah, Blackland Prairie, And Pineywoods Ecoregions Of Texas, Michael Tiller Dec 2021

Seasonal Flammability Comparisons Of Native And Exotic Plants In The Post Oak Savannah, Blackland Prairie, And Pineywoods Ecoregions Of Texas, Michael Tiller

Electronic Theses and Dissertations

East Texas’ diverse landscape can present year-round wildfire seasons that can be influenced by seasonal and regional differences in climate and physiography. Greater insight into the fundamental thermal behavior of wildland fuels can aid in fire behavior prediction and development of fire-resistant plant lists. This study focused on estimating seasonal and regional flammability characteristics of five evergreen species: yaupon (Ilex vomitoria), Chinese privet (Ligustrum sinense), greenbrier (Smilax spp.), eastern red cedar (Juniperus virginiana), and escarpment live oak (Quercus fusiformis); and two deciduous species: Chinese tallow (Triadica sebifera) and southern …

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The Effects Of Hydrologic Heterogeneity On Harmful Algal Blooms In Freshwater Reservoir, Lake Sinclair, Georgia, Margaret Blackledge Dec 2021

The Effects Of Hydrologic Heterogeneity On Harmful Algal Blooms In Freshwater Reservoir, Lake Sinclair, Georgia, Margaret Blackledge

Biology Theses

Aquatic habitats are frequently studied after a major water quality problem like the occurrence of an algal bloom. In this study, A proactive rather than a reactive response was considered, where the complexity of conditions conducive to uncontrolled cell growth were studied before a bloom took place by sampling regularly. This study aimed to monitor water quality by monthly sampling of algal communities for approximately one year. As the base of the aquatic food web, algae are a highly diverse group of organisms with varying sensitivity to physical and chemical changes in the environment. Four shallow sites were monitored at …

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Computationally Modeling Dynamic Biological Systems, Katherine Jarvis Dec 2021

Computationally Modeling Dynamic Biological Systems, Katherine Jarvis

Electronic Theses and Dissertations

Modeling biological systems furthers our understanding of dynamic relationships and helps us make predictions of the unknown properties of the system. The simple interplay between individual species in a dynamic environment over time can be modeled by equation-based modeling or agent- based modeling (ABM). Equation based modeling describes the change in species quantity using ordinary differential equations (ODE) and is dependent on the quantity of other species in the system as well as a predetermined rates of change. Unfortunately, this method of modeling does not model each individual agent in each species over time so individual dynamics are assumed to …

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Assessing The Potential For Lightning-Induced Damage In Commercial Broiler Houses In Mississippi And Alabama, Matthew R. Rowland Dec 2021

Assessing The Potential For Lightning-Induced Damage In Commercial Broiler Houses In Mississippi And Alabama, Matthew R. Rowland

Theses and Dissertations

Modern broiler houses are expensive to build, maintain, and insure. Protecting them from extreme weather events is a major concern to producers, integrators, and insurance companies. Lightning strikes can cause catastrophic fires and electrical damage and can lead to costly bird losses. A greater understanding of the impact of lightning on the commercial broiler industries of MS and AL is needed. The objectives of this research were collection of baseline resistance data for broiler houses and equipment in both states, and mapping lightning strike densities across MS and AL, evaluating annual, monthly, seasonal, and diurnal patterns. 63.5% of surveyed broiler …

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Element Contamination In Port Everglades – Preparing For Ecological Impacts, Laura White Dec 2021

Element Contamination In Port Everglades – Preparing For Ecological Impacts, Laura White

All HCAS Student Capstones, Theses, and Dissertations

Port dredging is of economic importance worldwide but its impacts to the marine environment through the remobilization of elemental contaminants are not well understood. A massive deepening and widening of Port Everglades, Florida, will begin in 2023. Contaminated sediment disturbed during the dredging process could be released and prove to be harmful to three coral reef tracks located beginning 1.5 miles away from the port. This study focused on identifying and quantifying 14 different trace elements: arsenic (As), cadmium (Cd), cobalt (Co), chromium (Cr), copper (Cu), mercury (Hg), lead (Pb), manganese (Mn), molybdenum (Mo), nickel (Ni), selenium (Se), tin (Sn), …

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Determining The Psychosocial Needs Of The Nurses Of Covid-19 Patients, Allison Stevens Dec 2021

Determining The Psychosocial Needs Of The Nurses Of Covid-19 Patients, Allison Stevens

ATU Theses and Dissertations 2021 - Present

Nurses are a vital element of the COVID-19 healthcare crisis and have been since the beginning of the COVID-19 response. The professional strain put on nurses included, but is not limited to: changing professional roles, rapidly changing policies and procedures, an influx of patients—particularly of high acuity, and change in workplace morale. However, nurses also had to carry the burdens of living as a member of society, family member, friend, community member, and above all, simply as a person surviving a pandemic themselves. With all of the stressors nurses have endured, it stands to reason that their psychosocial needs have …

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Linking Plot And Landscape Level Phenology, Alejandra Flores Dec 2021

Linking Plot And Landscape Level Phenology, Alejandra Flores

Open Access Theses & Dissertations

Plant phenology has become popularize since the 1990s to help understand the effects of climate change on vegetation, it is a way to study the patterns of leaf-out, flowering, and senescing of the life-cycle of the plant. The timing from start of season (SOS) to end-of-season (EOS) of plant leaf-out development has important implication on ecosystem productivity and carbon cycling across ecological scales from individual trees to whole regions. The need for plant phenology studies in dryland are highly anticipated, since they make up 40% of the terrestrial landscape and recently have shown the play an important role in the …

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How Are Agricultural Research Projects Conceiving Innovation? An Assessment Of The European Union Multi-Actor Projects, Samuel Brea Martinez-Collado Dec 2021

How Are Agricultural Research Projects Conceiving Innovation? An Assessment Of The European Union Multi-Actor Projects, Samuel Brea Martinez-Collado

Graduate Theses and Dissertations

Horizon research programs are the European Union’s lighthouse for innovation and research concerning the agri-food chain, the management of natural resources, and the bioeconomy. Their innovation strategy approach is one that pursues the practical application of the research via the collaboration of all actors involved. Such strategy is the reflection of a Multi-Actor Approach as their procedure to enhance innovation. This paper presents the main trends and directions 101 Multi-Actor Projects (MAPs) are following on said approach towards innovation. The analysis is based on the use of well-defined “pathways” and “measures” proposed in the Guidelines for Evaluation of Innovation in …

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Transport And Fate Of Phosphorus In The Nearshore Zone Of Lake Michigan, Nathan Van Ee Dec 2021

Transport And Fate Of Phosphorus In The Nearshore Zone Of Lake Michigan, Nathan Van Ee

Theses and Dissertations

Bioavailable phosphorus loads exported to Lake Michigan from the Milwaukee and Sheboygan River Watersheds appear to have increased in the last 40 years despite meeting total phosphorus (TP) loading goals set by the Great Lakes Water Quality Agreement (GLWQA).Overall, bioavailability of P delivered from the Milwaukee and Sheboygan Rivers was highest during the warmer months, which coincides with the nearshore nuisance algae growth season. However, first order loss rates of SRP calculated during baseflow recession were also greatest during the summer, suggesting that increased river residence time during the summer could reduce export of bioavailable P. Observations of phosphorus partitioning …

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Analytical Considerations And Methods For Comprehensive Analysis Of Bacterial Phospholipidomics Using Hilic-Ms/Ms, David Thomas Reeves Dec 2021

Analytical Considerations And Methods For Comprehensive Analysis Of Bacterial Phospholipidomics Using Hilic-Ms/Ms, David Thomas Reeves

Doctoral Dissertations

Omics technologies have rapidly evolved over the last half century through vast improvements in efficient extraction methodologies, advances in instrumentation for data collection, and a wide assortment of informatics tools to help deconvolute sample data sets. However, there are still untapped pools of molecules that warrant further analytical attention. As the frontline defense of the cell against exterior influences, the phospholipid membrane is key in structure, defense, and signaling, but current omics studies are only just now catching up to the potential hidden within cellular lipid profiles. Examination of shifts in phospholipid speciation and character could provide researchers with a …

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Perceptions Of High Achieving High School Students Regarding The Professionalization Of Teaching And Their Interest In Becoming Teachers, Jonathan Crossley Dec 2021

Perceptions Of High Achieving High School Students Regarding The Professionalization Of Teaching And Their Interest In Becoming Teachers, Jonathan Crossley

ATU Theses and Dissertations 2021 - Present

This study was designed to highlight the factors that contribute to high-achieving high school students not deciding to join the teaching profession. There is growing evidence to indicate that the teaching profession is comprised mostly of educators in their first five years in the profession and educators with more than 25 years of teaching experience. Increasing numbers of educators are leaving the profession within their first five years in a classroom. On the other end of the spectrum, as teachers with more than 25 years of experience ultimately retire, the question remains about the viability of the profession for younger …

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The Effects Of Commercial Harvest On The Density And Demography Of Aquatic Turtles In Arkansas, Andrhea Darleen Massey Dec 2021

The Effects Of Commercial Harvest On The Density And Demography Of Aquatic Turtles In Arkansas, Andrhea Darleen Massey

Graduate Theses and Dissertations

The United States is home to the second highest concentration of turtle species in the world, after Asia. As of 2018, there are 57 turtle species recognized within the US, 40% of which are listed as threatened or endangered, with the primary threats to population persistence identified as over-consumption and/or habitat loss. Within the US, the Mississippi Alluvial Valley (MAV) region represents the second highest turtle species richness, after the Mobile River Basin. The MAV region of Arkansas is one of the least regulated in terms of commercial aquatic turtle harvest and has undergone large-scale habitat conversion from bottomland hardwood …

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Nutrient Uptake And Management Strategies In Recirculating Hydroponic Systems, Lauren Leigh Houston Dec 2021

Nutrient Uptake And Management Strategies In Recirculating Hydroponic Systems, Lauren Leigh Houston

Graduate Theses and Dissertations

Nutrient management in recirculating hydroponic systems requires the periodic replenishment of water and nutrients to the nutrient solution reservoir. Common nutrient management strategies, such as replenishing the reservoir with fresh solution and maintaining a constant solution electrical conductivity (EC), can lead to ion accumulation and nutrient imbalances since nutrients are taken up by roots and depleted from solution at different rates. To avoid nutritional disorders, commercial growers typically dump and replace the hydroponic solution periodically, which is wasteful and has an economic cost. A potential alternative is to specially formulate the nutrient replenishment solution to balance the supply of nutrients …

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Impact Of Xenobiotics On Neuronal Outcomes, Gabriela Henriquez Dec 2021

Impact Of Xenobiotics On Neuronal Outcomes, Gabriela Henriquez

Open Access Theses & Dissertations

Neurodegenerative diseases are a common affliction of the Central Nervous System. They are caused by age, genetics, and environmental factors. Alzheimer's disease, Parkinson's disease, Huntington's disease, and Amyotrophic Lateral Sclerosis are well-known among the host of neurodegenerative disorders, with Alzheimer's disease and Parkinson's disease being the leading pathologies across this canvas. It is known that the pathogenesis of neurodegenerative diseases is multifactorial due to the involvement of genetic mutations, radical-induced protein damage, abnormal aggregation of misfolded proteins, and the formation of amyloid deposits. The amyloid proteins in neurodegenerative disease include Tau and Amyloid (Aβ) in Alzheimer's disease and α-Synuclein in …

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Economic Potash Fertilizer Rate Recommendations, Kimberly B. Oliver Dec 2021

Economic Potash Fertilizer Rate Recommendations, Kimberly B. Oliver

Graduate Theses and Dissertations

This thesis is comprised of two studies that estimate profit-maximizing potassium (K) fertilizer application rates for various crops across different time periods. Estimation of profit-maximizing fertilizer-K rate (K*) for both studies considered the initial soil test level of K (STK) and yield response information, as traditional recommendations do, and added crop price and the cost of fertilizer. Profit maximum occurs where the marginal revenue from additional yield is equal to the marginal cost of applying an additional unit of fertilizer-K. The first study calculated K* for corn (Zea mays) and cotton (Gossypium hirsutum) and compared results to previous studies on …

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Biotic Interactions At Species’ Range Limits In A Changing Climate, Isaac Shepard Dec 2021

Biotic Interactions At Species’ Range Limits In A Changing Climate, Isaac Shepard

Electronic Theses and Dissertations

As the global climate changes, many species are shifting their geographic ranges, often towards the poles or upslope in elevation. The ubiquity of these observation has renewed discussions about the mechanisms that determine species’ range margins. Leading hypotheses state abiotic variables should be the most important factor for setting range limits in environmentally stressful habitats. However, I propose an alternative hypothesis that biotic interactions may still be critically important for setting range limits, even in abiotically stressful habitats. Using a model system of ponds in the Rocky Mountains of Colorado, I developed several field experiments to empirically test the role …

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Cover Crop Effects On Near-Surface Soil Aggregate Stability In The Southern Mississippi Valley Loess (Mlra 134), Chandler M. Arel Dec 2021

Cover Crop Effects On Near-Surface Soil Aggregate Stability In The Southern Mississippi Valley Loess (Mlra 134), Chandler M. Arel

Crop, Soil and Environmental Sciences Undergraduate Honors Theses

Intensive agricultural cultivation within major land resource area (MLRA) 134, the Southern Mississippi Valley Loess, has led to soil erosion, soil compaction, and the overall destabilization of near-surface soil aggregates. The use of cover crops during the agricultural offseason has been shown to help alleviate soil compaction and provide stabilizing effects against soil erosion, which are particularly important as the silty soils of MLRA 134 have a large erosion potential. This study evaluated the effects of cover crop and no-cover crop treatment on silt-loam soils within MLRA 134. Treatments were implemented during Fall 2018 and Fall 2019 and consisted of …

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Intelligent Resource Prediction For Hpc And Scientific Workflows, Benjamin Shealy Dec 2021

Intelligent Resource Prediction For Hpc And Scientific Workflows, Benjamin Shealy

All Dissertations

Scientific workflows and high-performance computing (HPC) platforms are critically important to modern scientific research. In order to perform scientific experiments at scale, domain scientists must have knowledge and expertise in software and hardware systems that are highly complex and rapidly evolving. While computational expertise will be essential for domain scientists going forward, any tools or practices that reduce this burden for domain scientists will greatly increase the rate of scientific discoveries. One challenge that exists for domain scientists today is knowing the resource usage patterns of an application for the purpose of resource provisioning. A tool that accurately estimates these …

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The Electrification Of The Kitchen: On The Energy Consumption Of Common Electric Cooking Appliances, Hozen Ricchie Rose Asok Rose Dec 2021

The Electrification Of The Kitchen: On The Energy Consumption Of Common Electric Cooking Appliances, Hozen Ricchie Rose Asok Rose

Graduate Theses and Dissertations

In developed countries, electricity has been gaining popularity as a source of energy for meal preparation. Utilizing electricity produced from renewable resources along with efficient electrical cooking appliances could result in sustainable clean cooking. The first objective of this research was to study the efficiency of common electrical cooking appliances—namely induction, resistance plate, resistance coil, infrared, and electric pot— by the water boiling test and the simmering test. The induction and electric pot were observed as the most efficient devices for the water boiling test. For simmering, which mimics many cooking processes, the electric pot and resistance coil were the …

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Field Evaluation Of Struvite As A Phosphorus Source, Niyi Sunday Omidire Dec 2021

Field Evaluation Of Struvite As A Phosphorus Source, Niyi Sunday Omidire

Graduate Theses and Dissertations

Phosphorus (P) is an element that is crucial in many biological processes in all forms of life and is not substitutable. Excess P in wastewaters leading to the degradation of receiving waters or eutrophication once released is a major environmental concern. Removal of excess P from wastewater as the mineral struvite (MgNH4PO4·6H2O) could be a promising solution to reduce P discharge into receiving waters and can potentially provide a valuable fertilizer-P source for agricultural production. The objectives of this project were to evaluate the effects of: 1) chemically precipitated struvite (CPST), compared to triple superphosphate (TSP) and an unamended control …

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Body Mass And Body Condition Variation Of Mallards (Anas Platyrhynchos) Within And Among Winters Within The Lower Mississippi Alluvial Valley, John Thompson Veon Dec 2021

Body Mass And Body Condition Variation Of Mallards (Anas Platyrhynchos) Within And Among Winters Within The Lower Mississippi Alluvial Valley, John Thompson Veon

Graduate Theses and Dissertations

Most North American waterfowl overwinter in southern North America before migrating back to breeding grounds in the northern US and Canada. These species face the challenge of needing to maintain or increase their body mass during an environmentally difficult winter period. Successful body mass maintenance during the winter period has major ramifications not only for their winter survival but for their fitness across the entire year. Recent research in Europe and the western United States suggests that the body mass of mallards (Anas platyrhynchos) has increased from the late 1960s to early 2000s. However, the factors responsible for increases in …

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Effects Of Localized Oxygen Production By Electrolysis On The First-Generation Glucose Sensor Response, Nandita Halder Dec 2021

Effects Of Localized Oxygen Production By Electrolysis On The First-Generation Glucose Sensor Response, Nandita Halder

Graduate Theses and Dissertations

Glucose sensors are very important for detecting blood glucose both in vitro and in vivo. First-generation glucose biosensors were based on the glucose oxidase (GOx) enzyme using molecular oxygen as the electron acceptor and therefore oxygen dependent. Unfortunately for in-vivo work, oxygen in the body is variable and limited. Alternative approaches to overcome the oxygen dependency came with their own limitations. The widely used and commercially available ex-vivo glucose test strip uses a mediator in place of oxygen to free it from oxygen dependency. The mediator-based technology, in most cases cannot be transferred to in vivo applications due to the …

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Use Patterns And Influencing Factors Of Irrigation Best Management Practices In The Lower Mississippi River Basin, Merri E. Day Dec 2021

Use Patterns And Influencing Factors Of Irrigation Best Management Practices In The Lower Mississippi River Basin, Merri E. Day

Graduate Theses and Dissertations

This study uses the 2016 Irrigation Survey from Arkansas, Louisiana, and Mississippi to document the use of irrigation best management practices (IBMPs), analyze use patterns, and use quantitative methods to determine factors that influence producers’ decisions regarding IBMPs. IBMPs included in the survey can be grouped as: field management practices (zero-grade leveling, precision-grade leveling, end blocking, warped surface, and deep tillage), water flow control practices (computerized pipe-hole selection, multiple-inlet irrigation, surge irrigation, alternate wetting and drying, cutback irrigation, flow meters, and pump timers), water recovery/storage practices (tail-water recovery system and on-farm storage reservoir), and advanced irrigation scheduling practices (soil moisture …

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