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Full-Text Articles in Life Sciences
Lipophilic Probes For Cellular Ethylene Detection, Morgan R. Brown
Lipophilic Probes For Cellular Ethylene Detection, Morgan R. Brown
Electronic Theses and Dissertations
The structure of ethylene is simple, yet its biological effects are significant. When considering its role in biology it is almost exclusively regarded as a plant hormone. Research on ethylene from plants was progressed by several advancements in analytical instrumentation, from its discovery to elucidation of its signaling pathway. There is currently limited understanding of ethylene’s role in mammals, but evidence suggests that it may be a biomarker for oxidative stress! Additional tools and technology are crucial to study this surprising and important signaling role in mammals. Our group has developed molecular ethylene probes as a strategy to detect ethylene …
Soil Resilience And Arbuscular Mycorrhizal Fungi: How Fungi Can Inform Climate Change Mitigation And Adaptation In Maya Milpa Management, Courtney Mathers
Soil Resilience And Arbuscular Mycorrhizal Fungi: How Fungi Can Inform Climate Change Mitigation And Adaptation In Maya Milpa Management, Courtney Mathers
Electronic Theses and Dissertations
In Mexico’s state of Yucatán, climate change impacts like prolonged and less predictable dry season length are manifesting as threats to agricultural production and food security. Nearly two thirds of Yucatán’s population is indigenous, many of whom live in rural communities that rely on rainfed subsistence agriculture (INEGI 2015). Ensuring sufficient food production in the face of climate change relies on the quality of agricultural soils. With both mismanagement of agricultural soils and climate change posing as threats to food production in Mexico, soil management practices that increase a soil quality should be identified and promoted. The primary objective of …
Investigating Spatiotemporal Kinetics, Dynamics, And Mechanism Of Exosome Release, Anarkali Mahmood
Investigating Spatiotemporal Kinetics, Dynamics, And Mechanism Of Exosome Release, Anarkali Mahmood
Electronic Theses and Dissertations
Exosomes are small lipid-based vesicles that can carry biomolecules from one cell to another. While exosomes are crucial to maintain homeostasis in healthy cells, they are exploited by unhealthy cells to aid disease progression. Exosomes likely facilitate disease progression via the transfer of disease-causing biomolecules from unhealthy to healthy cells. Exosomes are generated in Multivesicular endosomes (MVEs) and are then secreted into the extracellular space to travel to other cells. Despite being a crucial step, very little is known about exosomes release mechanism and dynamics. To further our understanding of exosomes, specifically their secretion, my work has focused on investigating …