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Pharmacology, Toxicology and Environmental Health

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2018

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Articles 1 - 30 of 63

Full-Text Articles in Life Sciences

Profile Interview With Norman E. Fenn, Shannon L. Castek Nov 2018

Profile Interview With Norman E. Fenn, Shannon L. Castek

Purdue Journal of Service-Learning and International Engagement

Shannon L. Castek is a fourth-generation Boilermaker and fourth-professional-year student in the Purdue University College of Pharmacy. Throughout her time in pharmacy school, Shannon has enjoyed supplementing her curricular work with service-learning activities, participating in health screenings and immunization events with the Purdue chapter of the American Pharmacists Association–Academy of Student Pharmacists. She plans to pursue a pharmacy residency following graduation to achieve her dream of becoming an ambulatory care pharmacist. In this article, Shannon highlights the service-learning endeavors of Dr. Norman Fenn in the College of Pharmacy.


The Pharmaceutical Industry: A Pharmacy Student's Guide, Christian Egly, Yaman Kaakeh Nov 2018

The Pharmaceutical Industry: A Pharmacy Student's Guide, Christian Egly, Yaman Kaakeh

Purdue Journal of Service-Learning and International Engagement

Christian Egly is a fourth-year (P4) pharmacy student in the Purdue University College of Pharmacy. During his years at Purdue, he worked in labs performing bench research in clinical pharmacology and biochemistry. He plans to work in the pharmaceutical industry after graduation. During his fourth year, he completed rotations in business development at Kashiv Pharma, LLC, and was hired there for an internship in 2017. In the article, Christian describes his personal experiences at Kashiv Pharma, LLC, and how industry can positively affect patient communities.


Neurobehavioral Evaluation Of Mice Dosed With Water Hemlock Green Seeds And Tubers, Camila F. P. Orlando-Goulart, Kevin D. Welch, James A. Pfister, Daniel S. Goulart, Adilson D. Damasceno, Stephen T. Lee Oct 2018

Neurobehavioral Evaluation Of Mice Dosed With Water Hemlock Green Seeds And Tubers, Camila F. P. Orlando-Goulart, Kevin D. Welch, James A. Pfister, Daniel S. Goulart, Adilson D. Damasceno, Stephen T. Lee

Poisonous Plant Research (PPR)

Water hemlock are plants of the genus Cicuta and are toxic to animals and humans. The primary toxin is cicutoxin, which is abundant in the tubers, but less abundant in other parts of the plant. Other cicutoxin-like compounds, such as cicutols, which may also contribute to the toxicity of water hemlock, are more abundant in non-tuber plant parts. The objective of this study was to determine the toxicity of different parts of water hemlock and characterize their effects on motor function/coordination in mice. An aqueous extract of green seeds, dry seeds, tubers, flowers and stems of water hemlock was dosed …


A Review Of Inhalation Exposure To Mold And Adverse Health Outcomes, Amanda S. Persad, Todd Stedeford, Marek Banasik, Tomasz T. Suchecki, Carlos A. Muro-Cacho Aug 2018

A Review Of Inhalation Exposure To Mold And Adverse Health Outcomes, Amanda S. Persad, Todd Stedeford, Marek Banasik, Tomasz T. Suchecki, Carlos A. Muro-Cacho

Florida State University Journal of Land Use and Environmental Law

No abstract provided.


Mycotoxins: Mechanisms For Toxicity And Methods For Identifying Exposed Individuals, Carlos A. Muro-Cach, Todd Stedeford, Marek Banasik, Tomasz T. Suchecki, Amanda S. Persad Aug 2018

Mycotoxins: Mechanisms For Toxicity And Methods For Identifying Exposed Individuals, Carlos A. Muro-Cach, Todd Stedeford, Marek Banasik, Tomasz T. Suchecki, Amanda S. Persad

Florida State University Journal of Land Use and Environmental Law

No abstract provided.


Toxicology And Risk Assessment Of Mycotoxins, Raymond D. Harbison, Todd Stedeford, Marek Banasik, Carlos A. Muro-Cacho Aug 2018

Toxicology And Risk Assessment Of Mycotoxins, Raymond D. Harbison, Todd Stedeford, Marek Banasik, Carlos A. Muro-Cacho

Florida State University Journal of Land Use and Environmental Law

No abstract provided.


Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen Aug 2018

Yardwork: A Biography Of An Urban Place By Daniel Coleman, Vivian M. Hansen

The Goose

Review of Daniel Coleman's Yardwork: A Biography of an Urban Place.


The Right To Be Cold: One Woman’S Fight To Protect The Arctic And Save The Planet From Climate Change By Sheila Watt-Cloutier, Leah Van Dyk Aug 2018

The Right To Be Cold: One Woman’S Fight To Protect The Arctic And Save The Planet From Climate Change By Sheila Watt-Cloutier, Leah Van Dyk

The Goose

Review of Sheila Watt-Cloutier's The Right to Be Cold: One Woman's Fight to Protect the Arctic and Save the Planet from Climate Change.


Killi-Data News (Winter), Tyrone Genade Mar 2018

Killi-Data News (Winter), Tyrone Genade

Killifish Research Review

Valued readers, it is with a heavy heart that I inform you that this is the last issue of Killi-Data News. The good news is that we will be back as Killifish Research Review. The dissolution of Killi-Data International created a prob- lem: how can the newsletter of a defunct organization live on without that organization? But other additional problems were building in the background. The first issue numbered 15 pages. The previous issue was 28 pages. The number of killifish related papers is increasing while time on our end (the editorial team) is running out. It takes a lot …


Killi-Data News (Fall), Tyrone Genade Mar 2018

Killi-Data News (Fall), Tyrone Genade

Killifish Research Review

Many interesting papers have been published over the last three months. The large volume of papers coupled with the start of the new college semester (and the workload it brings) delayed this issue of Killi-Data News. But better late than never—or so I hope! In this issue Richard van der Laan provides an insightful review of the recent Aphanius papers as to their taxonomic implications and questions. The systematic issues he raises show the importance of the Molecular project: we need to get more samples of the various cyprinodontiforme families to resolve unsettled systematic and taxonomic issues. In the Next …


Killi-Data News (Summer), Tyrone Genade Mar 2018

Killi-Data News (Summer), Tyrone Genade

Killifish Research Review

Over the last three months several interesting and exciting pa- pers have been published. By now most of you have heard the Nothobranchius fish poo news emanating from the Valenzano lab. That paper is reviewed and certainly has repercussions for the health of our captive fish. Polaçik et al have published interesting data with ramifications as to how we breed and incubate annual killifish. The big news in this issue is the paper from the Reznick lab which Jean Huber reviews. The contents of that paper goes to the heart of the question of just what a killifish is. The …


Killi-Data News (Spring), Tyrone Genade Mar 2018

Killi-Data News (Spring), Tyrone Genade

Killifish Research Review

This is the start of Killi-Data News’ second year. In this first issue of the year we have the usual review of research pub- lications as well as input from Martin Reichard on his lab’s Nothobranchius research. Martin is responding to my reviews of his lab’s work in the previous edition. I am serious about making sure the content in this newsletter is reliable but I erred in the previous edition and Martin has written extensively to correct my mistake in the section “Erratum”. This reply is welcomed and owed to readers. I must confess that I don’t know everything …


Killi-Data News (Winter), Tyrone Genade Mar 2018

Killi-Data News (Winter), Tyrone Genade

Killifish Research Review

This is the fourth edition, and concluding issue of the first volume, of Killi-Data News and I am happy that it has been well received by readers. At 25 pages this issue is a bit thin- ner than the last but this is because we agreed to make the cut-off for submissions the 1 st of December so we could get this edition out by the New Year. This is an exciting edition full of new species descrip- tions and analyses that will keep taxonomists busy for years to come. Costa has given us two molecular phylogenies on Melanorivulus as …


Killi-Data News (Spring), Tyrone Genade Mar 2018

Killi-Data News (Spring), Tyrone Genade

Killifish Research Review

This is the start of Killi-Data News’ second year. In this first issue of the year we have the usual review of research pub- lications as well as input from Martin Reichard on his lab’s Nothobranchius research. Martin is responding to my reviews of his lab’s work in the previous edition. I am serious about making sure the content in this newsletter is reliable but I erred in the previous edition and Martin has written extensively to correct my mistake in the section “Erratum”. This reply is welcomed and owed to readers. I must confess that I don’t know everything …


Investigating Sociodemographic Disparities In Cancer Risk Using Web-Based Informatics, Hong-Jun Yoon, Georgia Tourassi Jan 2018

Investigating Sociodemographic Disparities In Cancer Risk Using Web-Based Informatics, Hong-Jun Yoon, Georgia Tourassi

Journal of Human Performance in Extreme Environments

Cancer health disparities due to demographic and socioeconomic factors are an area of great interest in the epidemiological community. Adjusting for such factors is important when developing cancer risk models. However, for digital epidemiology studies relying on online sources such information is not readily available. This paper presents a novel method for extracting demographic and socioeconomic information from openly available online obituaries. The method relies on tailored language processing rules and a probabilistic scheme to map subjects’ occupation history to the occupation classification codes and related earnings provided by the U.S. Census Bureau. Using this information, a case-control study is …


The Clean Air Act And Its Impact On Ground Level Ozone Pollution Levels In Los Angeles, California, Rebecca Ford Jan 2018

The Clean Air Act And Its Impact On Ground Level Ozone Pollution Levels In Los Angeles, California, Rebecca Ford

Bridges: A Journal of Student Research

Ozone (O3) occurs as a photochemically produced pollutant in the troposphere and its emission and concentration is regulated by the Clean Air Act (CAA) of 1970. The Los Angeles area is an example of how O3 can be a public health hazard and taint a city’s aesthetics and quality of life through photochemical smog. This study was conducted to observe the overall effectiveness of the CAA. I explored daily O3 concentrations from 1980 to the present at three air quality monitoring stations in LA from the AirData database of the U.S. Environmental Protection Agency. National O3 standards were only exceeded …


Population Pharmacokinetics Analysis Of Vancomycin In Critically Ill Patients, Wanchai Treyaprasert Jan 2018

Population Pharmacokinetics Analysis Of Vancomycin In Critically Ill Patients, Wanchai Treyaprasert

The Thai Journal of Pharmaceutical Sciences

Objectives: The aim of this study was to determine population pharmacokinetic parameters of vancomycin in adult critically ill patients and to investigate the covariates affecting population pharmacokinetic parameters. Methods: Plasma concentration data..


Bioactivities Of Organic Riceberry Broken Rice And Crude Riceberry Rice Oil, Vijitra Luang-In, Manatchanok Yotchaisarn, Issaraporn Somboonwatthanakul, Sirirat Deeseenthum Jan 2018

Bioactivities Of Organic Riceberry Broken Rice And Crude Riceberry Rice Oil, Vijitra Luang-In, Manatchanok Yotchaisarn, Issaraporn Somboonwatthanakul, Sirirat Deeseenthum

The Thai Journal of Pharmaceutical Sciences

Objectives: Riceberry broken rice (RBR) and crude riceberry rice oil (CRO) are inevitable by-products generated from organic rice process in Thailand for several tons per year with low value. The aims of this work were to determine gamma-oryzanol content.


Cost-Effectiveness Analysis Of Aripiprazole Compared With Risperidone In Treatment Of Acute Schizophrenia Patients In Thailand, Wiwat Thavornwattanayong Jan 2018

Cost-Effectiveness Analysis Of Aripiprazole Compared With Risperidone In Treatment Of Acute Schizophrenia Patients In Thailand, Wiwat Thavornwattanayong

The Thai Journal of Pharmaceutical Sciences

OBJECTIVES: Schizophrenia is the third leading cause of loss of life years in Thailand. Currently, aripiprazole is the latest drug for the treatment of acute schizophrenia in Thailand but its cost-effectiveness has not been studied. The purpose of this s.


Quick-Fat Diet Inhibits The Development Of Diabetes In Spontaneously Diabetic Torii (Sdt) Rats, Takeshi Ohta, Takahisa Yamada, Taiichiro Kamiya, Takayuki Gotoh, Masataka Tsubaki, Masami Shinohara Jan 2018

Quick-Fat Diet Inhibits The Development Of Diabetes In Spontaneously Diabetic Torii (Sdt) Rats, Takeshi Ohta, Takahisa Yamada, Taiichiro Kamiya, Takayuki Gotoh, Masataka Tsubaki, Masami Shinohara

The Thai Journal of Pharmaceutical Sciences

The diabetic animal model is very useful for developing functional foods and medicinal drugs. Spontaneously Diabetic Torii (SDT) rat, a non-obese type 2 diabetic model, is one of the hopeful models to play an important role for research and development o.


A Novel Assay For Evaluation Of The Total Antioxidant Capacity (Tac) Using A Nontoxic Probe, Sirirat Panich Jan 2018

A Novel Assay For Evaluation Of The Total Antioxidant Capacity (Tac) Using A Nontoxic Probe, Sirirat Panich

The Thai Journal of Pharmaceutical Sciences

A novel and simple method for measuring total antioxidant capacity (TAC) was established. Herein, the new assay is based on generating the deep blue Imipramine (IMI) free radical by oxidising IMI with ammonium tetra vanadate (NH4VO3) in acid medium. Once.


In Silico Evaluation Of Molecular Interactions Between Known ?-Glucosidase Inhibitors And Homologous ?-Glucosidase Enzymes From Saccharomyces Cerevisiae, Rattus Norvegicus, And Ganc-Human, Teni Ernawati Jan 2018

In Silico Evaluation Of Molecular Interactions Between Known ?-Glucosidase Inhibitors And Homologous ?-Glucosidase Enzymes From Saccharomyces Cerevisiae, Rattus Norvegicus, And Ganc-Human, Teni Ernawati

The Thai Journal of Pharmaceutical Sciences

The aim of this study was to observe molecular interactions between alpha glucosidase inhibitor waith alpha glucosidase enzyme derived from Saccharomyces cereviseae, Rattus norvegicus and GANC-human. Therefore, they were used against four of the well-kno.


Evaluating The Effect Of Donepezil On Depression And Obsessive–Compulsion Disorder In Mice Models And Proposing The Mechanism Involved, Azadeh Mesripour, Valiollah Hajhashemi, Shahrzad Rezaie Jan 2018

Evaluating The Effect Of Donepezil On Depression And Obsessive–Compulsion Disorder In Mice Models And Proposing The Mechanism Involved, Azadeh Mesripour, Valiollah Hajhashemi, Shahrzad Rezaie

The Thai Journal of Pharmaceutical Sciences

Introduction: Considering that donepezil (DPZ) is commonly prescribed for Alzheimer's disease patients, the aim of the present study was evaluating DPZ antidepressant effect and introducing the possible mechanism. Therefore nicotinic (mecamylamine) and m.


Anti-Hyperglycemic Effect And Subchronic Toxicity Of The Combined Extract From Sattagavata- Mathurameha -Tubpikarn Anti-Diabetic Herbal Formulae, Penchom Peungvicha Jan 2018

Anti-Hyperglycemic Effect And Subchronic Toxicity Of The Combined Extract From Sattagavata- Mathurameha -Tubpikarn Anti-Diabetic Herbal Formulae, Penchom Peungvicha

The Thai Journal of Pharmaceutical Sciences

The three herbal formulae (Sattagavata, Mathurameha, Tubpikarn) were prescribed to diabetic patients for a long times and they included Sattagavata for circulatory system promotion, Mathurameha for diabetics and Tubpikarn for hepatoprotection with less s.


Validated Thin-Layer Chromatography-Densitometric Method For Simultaneous Determination Of Piperine And Plumbagin In “Benjakul” Thai Polyherbal Formulation And Its Antioxidant Activities, Savita Chewchinda, Pattamapan Lomarat, Pongtip Sithisarn Jan 2018

Validated Thin-Layer Chromatography-Densitometric Method For Simultaneous Determination Of Piperine And Plumbagin In “Benjakul” Thai Polyherbal Formulation And Its Antioxidant Activities, Savita Chewchinda, Pattamapan Lomarat, Pongtip Sithisarn

The Thai Journal of Pharmaceutical Sciences

The purpose of this study was to evaluate antioxidant activity and quantitative analysis of piperine and plumbagin content in “Benjukul (BEN)” Thai polyherbal formulation by TLC densitometric method. BEN was recognized in the list of herbal medicinal...


Quantitative Structure–Activity Relationship Modeling Of S-Triazines And 2-Arylpyrimidines As Selective Pde4b Inhibitors, Anand Gaurav, Gabriel Akyirem Akowuah, Choo Shiuan Por Jan 2018

Quantitative Structure–Activity Relationship Modeling Of S-Triazines And 2-Arylpyrimidines As Selective Pde4b Inhibitors, Anand Gaurav, Gabriel Akyirem Akowuah, Choo Shiuan Por

The Thai Journal of Pharmaceutical Sciences

A QSAR analysis was conducted on a series of 2-arylpyrimidine and s-triazine derivatives as selective PDE4B inhibitors. Primary objective of the study is to develop predictive QSAR models for s-triazines and 2-arylpyrimidines as selective PDE4B and to id.


Effect Of Ipomoea Hederacea Jacq. Methanolic Extract On Blood Pressure And Relaxation Of Rat Thoracic Aorta: Evidence Indicated The Release Of No And H2s, Chaweewan Jansakul Jan 2018

Effect Of Ipomoea Hederacea Jacq. Methanolic Extract On Blood Pressure And Relaxation Of Rat Thoracic Aorta: Evidence Indicated The Release Of No And H2s, Chaweewan Jansakul

The Thai Journal of Pharmaceutical Sciences

Seeds of Ipomoeahederacea Jacq. (IH) are used in traditional medicine to manage ailments pertaining to the vasculature, circulatory system and related disorders. However no study exists to validate their usage for said ailments. The present study was con.


Antihypercholesterol Activity Of Costus Speciosus Water Extract, Hari Susanti, Subagus Wahyuono, Ratna Asmah Susidarti, Ika Puspita Sari Jan 2018

Antihypercholesterol Activity Of Costus Speciosus Water Extract, Hari Susanti, Subagus Wahyuono, Ratna Asmah Susidarti, Ika Puspita Sari

The Thai Journal of Pharmaceutical Sciences

Hypercholesterol is one of cause of cardiovascular disease. Costus speciosus is known empirically as an antihypercholesterol remedy. The study was conducted to determine the effect of water extract of Costus speciosus (CS) on cholesterol blood serum leve.


Antioxidant Potential Of Wild Lagenaria Siceraria (Molina) Standl, Suraj B. Patel, Usmangani A. Attar, S G. Ghane Jan 2018

Antioxidant Potential Of Wild Lagenaria Siceraria (Molina) Standl, Suraj B. Patel, Usmangani A. Attar, S G. Ghane

The Thai Journal of Pharmaceutical Sciences

Objective: The aim of the present study was to evaluate the phytochemicals and antioxidant activity of leaf and fruit of wild Bottle gourd. Methods: Successive extraction of dried material was done by soxhlet apparatus and phytochemicals such as total p..


Ethical Cases On Pharmacy Profession Practice In Thailand During A.D. 1995 To 2015, Wanna Sriviriyanupap, Usawadee Sutapuk Jan 2018

Ethical Cases On Pharmacy Profession Practice In Thailand During A.D. 1995 To 2015, Wanna Sriviriyanupap, Usawadee Sutapuk

The Thai Journal of Pharmaceutical Sciences

Background: Code of ethics for the pharmacy profession was established to enforce all pharmacists to abide by a rule for a good pharmacy professional practice. Objective: to study the ethical problems, related to the pharmacy profession practice, and to .