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Shuxuening Injection Facilitates Neurofunctional Recovery Via Down-Regulation Of G-Csf-Mediated Granulocyte Adhesion And Diapedesis Pathway In A Subacute Stroke Mouse Model, Zhixiong Li, Guangxu Xiao, Ming Lyu, Yule Wang, Shuang He, Hongxia Du, Xintong Wang, Benjamin Feng, Yan Zhu
Shuxuening Injection Facilitates Neurofunctional Recovery Via Down-Regulation Of G-Csf-Mediated Granulocyte Adhesion And Diapedesis Pathway In A Subacute Stroke Mouse Model, Zhixiong Li, Guangxu Xiao, Ming Lyu, Yule Wang, Shuang He, Hongxia Du, Xintong Wang, Benjamin Feng, Yan Zhu
Peer Reviewed Articles
Post-stroke neural damage is a serious health concern which does not yet have an effective treatment. We have shown previously that Shuxuening injection (SXNI), a Ginkgo biloba extract-based natural medicine, protects brain after an acute ischemic stroke, but its efficacy for post-stroke recovery is not known. This study was to investigate whether SXNI can improve the prognosis of stroke at a subacute phase. Mice with cerebral ischemia-reperfusion injury (CIRI) were established by middle cerebral artery occlusion (MCAO), and drugs or saline were injected by the tail vein every 12 h after reperfusion. The therapeutic effect of SXNI was evaluated by …