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Articles 1 - 30 of 36
Full-Text Articles in Life Sciences
Comparative Evaluation Of The Effects Of N-Hexane, Chloroform, And Methanol Fractions Of Ricinus Communis In Carbon Tetrachloride-Induced Hepatotoxic Rats, Matthew Obaineh Ojezele
Comparative Evaluation Of The Effects Of N-Hexane, Chloroform, And Methanol Fractions Of Ricinus Communis In Carbon Tetrachloride-Induced Hepatotoxic Rats, Matthew Obaineh Ojezele
The Thai Journal of Pharmaceutical Sciences
Background: Ricinus communis is widely used among the Nigerian populace in ethnomedicine for the treatment of liver diseases. Aim of the Study: A comparative study was carried out to evaluate the hepatoprotective activity of its n-hexane, chloroform, and.
Pharmacokinetics Of 8 Mg Galantamine Hydrobromide Prolonged-Release Capsules Under Fed And Fasting Conditions, Chuleegone Sornsuvit, Narawadee Niamhun, Parichat Salee, Darunee Hongwiset, Songwut Yotsawimonwat, Chockchai Wongsinsup
Pharmacokinetics Of 8 Mg Galantamine Hydrobromide Prolonged-Release Capsules Under Fed And Fasting Conditions, Chuleegone Sornsuvit, Narawadee Niamhun, Parichat Salee, Darunee Hongwiset, Songwut Yotsawimonwat, Chockchai Wongsinsup
The Thai Journal of Pharmaceutical Sciences
Objective: The objective of the study was to determine the pharmacokinetics of 8 mg galantamine prolonged-release capsules under fed and fasting conditions. Materials and Methods: A randomized, open-label, single-dose, two-treatment, two-period, two-sequ.
Anticonvulsant Activity Of Fumaria Schleicheri Dry Extract And Sodium Valproate: Role Of Neurotrophin And Cytokine Pathways, Vadim Tsyvunin, Sergiy Shtrygol, Tetiana Gorbatch, Diana Shtrygol
Anticonvulsant Activity Of Fumaria Schleicheri Dry Extract And Sodium Valproate: Role Of Neurotrophin And Cytokine Pathways, Vadim Tsyvunin, Sergiy Shtrygol, Tetiana Gorbatch, Diana Shtrygol
The Thai Journal of Pharmaceutical Sciences
Introduction: Cytokine and neurotrophin pathways can be potential targets for principally new anticonvulsant drugs which in perspective will be probably able to solve the problem of pharmacological resistance for people sick with epilepsy and to avoid po.
Synthesis, Evaluation, And In Silico Studies Of 2-Mercapto-5-Substituted Styryl-1,3,4-Oxadiazoles As Potential Cytotoxic Agents, Anitha Kumari Vinjavarapu, Shaheen Begum, Bharathi Koganti
Synthesis, Evaluation, And In Silico Studies Of 2-Mercapto-5-Substituted Styryl-1,3,4-Oxadiazoles As Potential Cytotoxic Agents, Anitha Kumari Vinjavarapu, Shaheen Begum, Bharathi Koganti
The Thai Journal of Pharmaceutical Sciences
Objective: The objective of the present study is to design, synthesize and evaluate 2-mercapto-5-styryl-1,3,4-oxadiazoles with an aim of developing potential cytotoxic agents and to carryout in silico studies to understand the possible interactions with .
In Silico Discovery Of Potential Diagnostic Biomarkers Of Lung Cancer, Ruzianisra Mohamed, Raja Nur Hidayah Raja Hasnan
In Silico Discovery Of Potential Diagnostic Biomarkers Of Lung Cancer, Ruzianisra Mohamed, Raja Nur Hidayah Raja Hasnan
The Thai Journal of Pharmaceutical Sciences
Introduction: Understanding hub genes implicated in lung cancer (LC) metastasis will help in finding effective ways to diagnose and cure cancer. Accurate identification of protein biomarkers helps in improving the prognosis of LC. Here, the focus of this.
Development Of Health-Related Quality Of Life Questionnaire For Patients On Continuous Drug Use, Wanna Tangpakdeerat, Rungpetch Sakulbumrungsil
Development Of Health-Related Quality Of Life Questionnaire For Patients On Continuous Drug Use, Wanna Tangpakdeerat, Rungpetch Sakulbumrungsil
The Thai Journal of Pharmaceutical Sciences
Background: Health-Related Quality of Life (HRQoL) instruments has become as a principal indicator of the effectiveness of medication treatment especially in case of lifelong therapy. Objectives: The purposes of the study were to develop a quality of lif.
A Comparison Of Model Fitting Using Different Runs In Box–Behnken Design For Alginate Film Formulation, Nichayarach Invichian N/A, Warangkana Warisnoicharoen
A Comparison Of Model Fitting Using Different Runs In Box–Behnken Design For Alginate Film Formulation, Nichayarach Invichian N/A, Warangkana Warisnoicharoen
The Thai Journal of Pharmaceutical Sciences
Introduction: Box–Behnken design (BBD) is a response surface method used for experimental design in several applications such as pharmaceutical and food. BBD experiment can be run using different central points (CPs) for analyzing optimal model fitting...
Anthelmintic Activity Of Mansoa Alliacea Against Pheretima Posthuma: In Vitro And In Silico Approach, D.S. N. B. K. Prasanth, S. K. Aminabee, Atmakuri Lakshmana Rao, Nayudu Teja, Koti Bhargavi, Chigurupati Monika, Boppudi Pujitha, Tera Sandhya, Agastya Lalitha, Siva Prasad Panda
Anthelmintic Activity Of Mansoa Alliacea Against Pheretima Posthuma: In Vitro And In Silico Approach, D.S. N. B. K. Prasanth, S. K. Aminabee, Atmakuri Lakshmana Rao, Nayudu Teja, Koti Bhargavi, Chigurupati Monika, Boppudi Pujitha, Tera Sandhya, Agastya Lalitha, Siva Prasad Panda
The Thai Journal of Pharmaceutical Sciences
Objectives: Mansoa alliacea has been utilized to remedy many afflictions of humans. Literary works illustrate that it possesses numerous biological activities. Our analysis work aims to distinguish phyto-derived anthelmintic substances from M. alliacea a.
Cell Viability Enhancing And Cellular Protection Activity Of Vitex Glabrata R.Br. Crude Fruits Extract On Tk6 And L929 Cell Lines, Saraphorn Intarasam, Thatchaphon Meemin, Mesayamas Kongsema, Kantimanee Pradermwong
Cell Viability Enhancing And Cellular Protection Activity Of Vitex Glabrata R.Br. Crude Fruits Extract On Tk6 And L929 Cell Lines, Saraphorn Intarasam, Thatchaphon Meemin, Mesayamas Kongsema, Kantimanee Pradermwong
The Thai Journal of Pharmaceutical Sciences
Studying the plant-based traditional medicine is a starting point for the advancement of modern studies. Vitex glabrata (VG) or Khai-Noa is a medicinal plant in Thailand, which fruits have been used by Thai ancients to improve cognition and enhance memor.
Spectrophotometric Estimation Of Linagliptin Using Ion-Pair Complexation And Oxidative Coupling Reactions – A Green Approach, Sunitha Gurrala, Panikumar Durga Anumolu, Sahitya Menkana, Nikitha Gandla, Keerthi Toddi
Spectrophotometric Estimation Of Linagliptin Using Ion-Pair Complexation And Oxidative Coupling Reactions – A Green Approach, Sunitha Gurrala, Panikumar Durga Anumolu, Sahitya Menkana, Nikitha Gandla, Keerthi Toddi
The Thai Journal of Pharmaceutical Sciences
Background: Two specific spectrophotometric methods (visible region) have been established using water as a solvent and validated for the analysis of linagliptin in API and pharmaceutical dosage forms. Materials and Methods: Method-A is established on th.
Proton Pump Inhibitors Use In Short Bowel Patients At A Thai Tertiary Hospital: A 10-Year Retrospective Observational Study, Sasisom Phadungkingtrakul, Namthip Iamkaeo, Piyathida Isutsiri, Prattana Sirisupamongkhon, Suyanee Pongthananikorn, Tippawan Siritientong
Proton Pump Inhibitors Use In Short Bowel Patients At A Thai Tertiary Hospital: A 10-Year Retrospective Observational Study, Sasisom Phadungkingtrakul, Namthip Iamkaeo, Piyathida Isutsiri, Prattana Sirisupamongkhon, Suyanee Pongthananikorn, Tippawan Siritientong
The Thai Journal of Pharmaceutical Sciences
Background: Proton pump inhibitors (PPIs) reduce the gastric acid secretion in short bowel patients. However, the absorptive areas of these patients are limited. In case of residual jejunum length <50 cm, the intravenous administration of PPIs should be .
Poly(Lactic-Co-Glycolic Acid) - Polyethylene Glycol Copolymer For Long-Acting Injectable: Synthesis, Characterization, And In-Vivo Study, Ravindra Kamble, Manasi Kulkarni, Swati Korake, Abhishek Pawar, Krishnat Dhekale
Poly(Lactic-Co-Glycolic Acid) - Polyethylene Glycol Copolymer For Long-Acting Injectable: Synthesis, Characterization, And In-Vivo Study, Ravindra Kamble, Manasi Kulkarni, Swati Korake, Abhishek Pawar, Krishnat Dhekale
The Thai Journal of Pharmaceutical Sciences
Aim: This work was aimed to develop a carrier system of poly(lactic-co-glycolic acid) (PLGA) by using polyethylene glycol (PEG) for longer action in various diseases by preparing a di-block copolymer by using Risperidone (RSP) as a drug. Methodology: PLG.
Measuring The Potential Antioxidant Activity Of Methyl Gallate: Molecular Docking Study, Sutomo S, Mohammad Rizki Fadhil Pratama
Measuring The Potential Antioxidant Activity Of Methyl Gallate: Molecular Docking Study, Sutomo S, Mohammad Rizki Fadhil Pratama
The Thai Journal of Pharmaceutical Sciences
Objectives: This study aims to obtain predictions of the interactions that occur between methyl gallate and various antioxidant receptors while comparing it with gallic acid as its parent compound. Materials and Methods: The protein crystal structures of.
Development And Evaluation Of Gastroretentive Formulations For Moxifloxacin Hydrochloride, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
Development And Evaluation Of Gastroretentive Formulations For Moxifloxacin Hydrochloride, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
The Thai Journal of Pharmaceutical Sciences
Purpose: The objective of the current study is to develop gastroretentive formulation for moxifloxacin HCl (hydrochloride) using various drug release modifiers and performing in vitro and in vivo evaluations. Moxifloxacin is a novel synthetic compound ha.
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
Assessment Of Antimicrobial Activity Of Moxifloxacin.Hcl From Gastro Retentive Formulations, Raghavendra Kumar Gunda, A. Vijayalakshmi, K. Masilamani
The Thai Journal of Pharmaceutical Sciences
Purpose: The objective of the present study is to assess the antimicrobial activity of gastroretentive formulation for moxifloxacin HCl and in vitro antimicrobial evaluation using the cup-plate method. Materials and Methods: Gastroretentive floating tabl.
Development And Validation Of Rp-Hplc Method For Simultaneous Determination Of Ondansetron Hydrochloride And Granisetron Hydrochloride In Their Admixtures With Pantoprazole Sodium, Al Montaser Hamed Bellah, Abdel Maaboud Ismail Mohamed, Niveen Abdel-Latif Mohamed
Development And Validation Of Rp-Hplc Method For Simultaneous Determination Of Ondansetron Hydrochloride And Granisetron Hydrochloride In Their Admixtures With Pantoprazole Sodium, Al Montaser Hamed Bellah, Abdel Maaboud Ismail Mohamed, Niveen Abdel-Latif Mohamed
The Thai Journal of Pharmaceutical Sciences
Objective: Development of rapid and sensitive high-performance liquid chromatography method for the quantification of ondansetron hydrochloride and granisetron hydrochloride in their admixtures with pantoprazole sodium in its dosage form using ketorolac .
Optimizing The Method For Quantification Of Apigenin And Quercetin In The Thai Herbal Sattakavata Formula By Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometer, Khuannara Narajeenrone, Jantanee Wattanarangsan, Kajee Pilakasiri, Pravit Akarasereenont, Suksalin Booranasubkajorn
Optimizing The Method For Quantification Of Apigenin And Quercetin In The Thai Herbal Sattakavata Formula By Ultra-Performance Liquid Chromatography Coupled With Mass Spectrometer, Khuannara Narajeenrone, Jantanee Wattanarangsan, Kajee Pilakasiri, Pravit Akarasereenont, Suksalin Booranasubkajorn
The Thai Journal of Pharmaceutical Sciences
Introduction: Sattakavata formula (SVF) is a Thai traditional medicine from Ayurved Siriraj for a relief of joint pain. It comprises six ingredients, namely, Andrographis paniculata (Burm. F.) Wall. ex Nees (AP), Cinnamomum sp. (CN), Morus alba Linn. (MA.
Anti-Tyrosinase And Anti-Melanogenic Potential Of Shallots (Allium Ascalonicum) From Various Cultivation Sites In Thailand, Thidarat Phetmanee, Thaniya Wunnakup, Thitiya Lukkunaprasit, Fameera Madaka, Sukanya Settharaksa, Narisa Kamkaen, Nirun Vipunnqeun, Laksana Charoenchai
Anti-Tyrosinase And Anti-Melanogenic Potential Of Shallots (Allium Ascalonicum) From Various Cultivation Sites In Thailand, Thidarat Phetmanee, Thaniya Wunnakup, Thitiya Lukkunaprasit, Fameera Madaka, Sukanya Settharaksa, Narisa Kamkaen, Nirun Vipunnqeun, Laksana Charoenchai
The Thai Journal of Pharmaceutical Sciences
Objectives: The present study aimed to investigate the anti-tyrosinase effect of shallots (Allium ascalonicum) in Thailand and to prepare an optimised shallot extract for use as a skin-lightening agent. Materials and Methods: Aqueous and ethanolic shallo.
Progress In Erectile Dysfunction Therapy Through Drug Delivery System, Mayuri Shitole, Shailesh Dugam, Rahul Tade, Neha Desai, Sopan Nangare
Progress In Erectile Dysfunction Therapy Through Drug Delivery System, Mayuri Shitole, Shailesh Dugam, Rahul Tade, Neha Desai, Sopan Nangare
The Thai Journal of Pharmaceutical Sciences
A man’s aptitude to acquire and continue an erection is frequently equated with masculinity and virility and can greatly influence men’s confidence. The sexual healthiness is a significant determinant of the worth of life. Erectile dysfunction (ED) a...
Ocimum Gratissimum Linn. (Lamiaceae) Protects Wistar Rats Against Inflammation And Oxidative Stress In Trinitrobenzene Sulfonic Acid-Induced Colitis, O. O. Abiodun, N. Nwadike, F. N. Ogunleye, A. S. Sosanya
Ocimum Gratissimum Linn. (Lamiaceae) Protects Wistar Rats Against Inflammation And Oxidative Stress In Trinitrobenzene Sulfonic Acid-Induced Colitis, O. O. Abiodun, N. Nwadike, F. N. Ogunleye, A. S. Sosanya
The Thai Journal of Pharmaceutical Sciences
Background and Aim: The activity of methanol extract of leaf of Ocimum gratissimum a plant with anti-inflammatory, antioxidant, and anti-ulcerogenic activities in a rat model of colitis was evaluated. Experimental Procedures: Colitis was induced in 30 of.
Monodora Myristica Seed Extracts Ameliorate Crude Oil Contaminated Diet-Induced Cardiotoxicity In Rats, G. T. Esiekpe, B. O. George, O. C. Orororo, A. A. Akpede, G. E. Okevwe, E. Onotugoma, J. Oguntola
Monodora Myristica Seed Extracts Ameliorate Crude Oil Contaminated Diet-Induced Cardiotoxicity In Rats, G. T. Esiekpe, B. O. George, O. C. Orororo, A. A. Akpede, G. E. Okevwe, E. Onotugoma, J. Oguntola
The Thai Journal of Pharmaceutical Sciences
Aim: This study investigated the ameliorative effects of Monodora myristica seed extracts in serum and heart of rats fed crude petroleum oil-polluted diet (CPOPD). ). Materials and Methods: Thirty adult Wistar rats (180 ± 5 g) were used for the study. T..
Development Of Immunofet Biosensor For Detection Of 3-Nitrotyrosine, Khine Kyi Han, Supachoke Mangmool, Korbtham Sathirakul, Kosum Chansiri, Wutthinan Jeamsaksiri, Prapimpun Wongchitrat, Montri Yasawong
Development Of Immunofet Biosensor For Detection Of 3-Nitrotyrosine, Khine Kyi Han, Supachoke Mangmool, Korbtham Sathirakul, Kosum Chansiri, Wutthinan Jeamsaksiri, Prapimpun Wongchitrat, Montri Yasawong
The Thai Journal of Pharmaceutical Sciences
3-Nitrotyrosine (3-NT) is one of the important biomarkers for the detection of excess of oxidative and nitrosative stress in the body, and derived from peroxynitrite-induced nitration of free and protein-bound at tyrosine residues. It was increased with .
Chemical Composition Of The Essential Oil Of Several Iris Species, Olha Mykhailenko N/A, Volodymyr Kovalyov, Tetyana Orlova
Chemical Composition Of The Essential Oil Of Several Iris Species, Olha Mykhailenko N/A, Volodymyr Kovalyov, Tetyana Orlova
The Thai Journal of Pharmaceutical Sciences
The essential oil was obtained by a steam distillation from the dried leaves of Iris germanica L., Iris versicolor L., Iris graminea L., and Iris halophila Pall. (Iridaceae) and was investigated by a gas chromatography-mass spectrometry (GC/MS) method. I.
Conditioned Medium Of Lipopolysaccharide-Treated Embryonic Stem Cell-Derived Mesenchymal Stem Cells Modulates In Vitro Secretion Of Inflammatory Cytokines, Faezeh Maghsood, Behrooz Johari, Nastaran Mohammadi Ghahhari, Mohammad Moradi, Mehdi Kadivar
Conditioned Medium Of Lipopolysaccharide-Treated Embryonic Stem Cell-Derived Mesenchymal Stem Cells Modulates In Vitro Secretion Of Inflammatory Cytokines, Faezeh Maghsood, Behrooz Johari, Nastaran Mohammadi Ghahhari, Mohammad Moradi, Mehdi Kadivar
The Thai Journal of Pharmaceutical Sciences
Background: The immunomodulatory properties of mesenchymal stem cells (MSCs) secretome have been considered by many investigators, and several preconditioning strategies such as pharmaceutical preconditioning have shown to strengthen the immunomodulatory.
Training Needs Of Thai Community Pharmacists For Primary Care Pharmacy: Qualitative Exploration, Surangkana Puengrung, Suntaree Watcharadamrongkun, Win Winit-Watjana
Training Needs Of Thai Community Pharmacists For Primary Care Pharmacy: Qualitative Exploration, Surangkana Puengrung, Suntaree Watcharadamrongkun, Win Winit-Watjana
The Thai Journal of Pharmaceutical Sciences
Introduction: Primary care pharmacy is crucial for community pharmacists and requires special training for some services. Objective: This study aims to explore current training needs of community pharmacists for primary care pharmacy using the Organizati.
The Effect And Cost Of Smoking Cessation Services Provided By Community Pharmacists In Thailand: A Descriptive Study Approach, Sunee Lertsinudom, Nadthatida Hansuri, Ampornpan Theeranut, Piyameth Dilokthornsakul
The Effect And Cost Of Smoking Cessation Services Provided By Community Pharmacists In Thailand: A Descriptive Study Approach, Sunee Lertsinudom, Nadthatida Hansuri, Ampornpan Theeranut, Piyameth Dilokthornsakul
The Thai Journal of Pharmaceutical Sciences
Introduction: The effect and cost of smoking cessation provided by pharmacists was varied and important for policy decision making. Aims: The aim of the study was to estimate the effect and cost of smoking cessation provided by community pharmacists in T.
Association Of N-Acetyltransferase 2 (Nat2) Polymorphisms And Elevated Liver Enzymes Of Myanmar Tuberculosis Patients In Thailand, Khin Sandi Thaw, Chanchira Choppradit, Pornpimol Kijsanayotin, Ratchanee Rodsiri
Association Of N-Acetyltransferase 2 (Nat2) Polymorphisms And Elevated Liver Enzymes Of Myanmar Tuberculosis Patients In Thailand, Khin Sandi Thaw, Chanchira Choppradit, Pornpimol Kijsanayotin, Ratchanee Rodsiri
The Thai Journal of Pharmaceutical Sciences
Isoniazid (INH) and its toxic metabolites are the major cause of anti-tuberculosis (TB) druginduced liver injury (AT-DILI). N-acetyltransferase 2 (NAT2) is involved in many metabolic pathways of INH. Previous studies demonstrated the association of NAT2 .
Protective Effect Of Croton Zambesicus Leaf Extract Against Carbon Tetrachlorideinduced Cardiac Toxicity In Rats, Rashidat Oluwafunke Ayanniyi, Hidayah Ayodeji Olumoh-Abdul, Fatimoh Idowu Ojuade, Nnaemeka Asogwa
Protective Effect Of Croton Zambesicus Leaf Extract Against Carbon Tetrachlorideinduced Cardiac Toxicity In Rats, Rashidat Oluwafunke Ayanniyi, Hidayah Ayodeji Olumoh-Abdul, Fatimoh Idowu Ojuade, Nnaemeka Asogwa
The Thai Journal of Pharmaceutical Sciences
Background: The leaves of Croton zambesicus (CZ) Muell Arg. (Euphorbiaceae) are used as a spice for food and in traditional medicine for the management of several disease conditions, including hypertension and diabetes. The study was carried out to deter.
Tumor Suppressive Effect Of Artemisia Annua Extract In 7, 12-Dimethylbenz[A]Anthracene-Induced Breast Cancer In Wistar Rats, Hemmat M.M. Faheem, Sameh M. M. El Nabtity, Mohamed A. M. Nassan
Tumor Suppressive Effect Of Artemisia Annua Extract In 7, 12-Dimethylbenz[A]Anthracene-Induced Breast Cancer In Wistar Rats, Hemmat M.M. Faheem, Sameh M. M. El Nabtity, Mohamed A. M. Nassan
The Thai Journal of Pharmaceutical Sciences
Objective: This study aimed to detect the genetic and immunohistochemical effects of the extract of Artemisia annua, a popular medicinal herb in a chemical model of breast cancer. Materials and Methods: Breast cancer was induced in female rats by 7, 12-d.
Cytotoxicity And Antiplasmodial Activity Of Alkaloid Extracts Prepared From Eight African Medicinal Plants Used In Nigeria, U. E. Uzuegbu, O. A. Opajobi, J. E. Utalor, C. O. Elu, I. Onyesom
Cytotoxicity And Antiplasmodial Activity Of Alkaloid Extracts Prepared From Eight African Medicinal Plants Used In Nigeria, U. E. Uzuegbu, O. A. Opajobi, J. E. Utalor, C. O. Elu, I. Onyesom
The Thai Journal of Pharmaceutical Sciences
Objectives: Malaria morbidity and mortality rates are worsening, despite the dedicated commitment to eradicate the infestation, principally because of failing chemotherapy, the mainstay of treatment, and lack of registered vaccine. Therefore, the search .