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Investigation Of Association Of Chemical Profiles With The Tracheobronchial Relaxant Activity Of Chinese Medicinal Herb Beimu Derived From Various Fritillaria Species., Xu Wu, Shun-Wan Chan, Jiang Ma, Ping Li, Pang-Chui Shaw, Ge Lin Jan 2018

Investigation Of Association Of Chemical Profiles With The Tracheobronchial Relaxant Activity Of Chinese Medicinal Herb Beimu Derived From Various Fritillaria Species., Xu Wu, Shun-Wan Chan, Jiang Ma, Ping Li, Pang-Chui Shaw, Ge Lin

Faculty of Science & Technology (THEi)

Ethnopharmacological relevance Fritillariae Bulbus (Beimu in Chinese) is derived from the bulbus of many Fritillaria species (family Liliaceae), which has been used as an antitussive herb in traditional Chinese medicine for more than 2000 years. Due to the complexity of plant origins and significant variations in chemical profiles, the characterization of the profile of the major bioactive constituents and its association with pharmacological activity are important for the quality control of Beimu herbs from different origins. Aim of the study This study aims to investigate the distribution of major bioactive isosteroidal alkaloids in Beimu herbs of different origins and its …