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Full-Text Articles in Life Sciences

Integration Of Random Forest Classifiers And Deep Convolutional Neural Networks For Classification And Biomolecular Modeling Of Cancer Driver Mutations, Steve Agajanian, Odeyemi Oluyemi, Gennady M. Verkhivker Jun 2019

Integration Of Random Forest Classifiers And Deep Convolutional Neural Networks For Classification And Biomolecular Modeling Of Cancer Driver Mutations, Steve Agajanian, Odeyemi Oluyemi, Gennady M. Verkhivker

Mathematics, Physics, and Computer Science Faculty Articles and Research

Development of machine learning solutions for prediction of functional and clinical significance of cancer driver genes and mutations are paramount in modern biomedical research and have gained a significant momentum in a recent decade. In this work, we integrate different machine learning approaches, including tree based methods, random forest and gradient boosted tree (GBT) classifiers along with deep convolutional neural networks (CNN) for prediction of cancer driver mutations in the genomic datasets. The feasibility of CNN in using raw nucleotide sequences for classification of cancer driver mutations was initially explored by employing label encoding, one hot encoding, and embedding to …


Using Multi-Indices Approach To Quantify Mangrove Changes Over The Western Arabian Gulf Along Saudi Arabia Coast, Wenzhao Li, Hesham El-Askary, Mohamed A. Qurban, Jingjing Li, K. P. Manikandan, Thomas Piechota Mar 2019

Using Multi-Indices Approach To Quantify Mangrove Changes Over The Western Arabian Gulf Along Saudi Arabia Coast, Wenzhao Li, Hesham El-Askary, Mohamed A. Qurban, Jingjing Li, K. P. Manikandan, Thomas Piechota

Mathematics, Physics, and Computer Science Faculty Articles and Research

Mangroves habitat present an important resource for large coastal communities benefiting from activities such as fisheries, forest products and clean water as well as protection against coastal erosion and climate related extreme events. Yet they are increasingly threatened by natural pressure and anthropogenic activities. We observed an inaccurate distribution of mangroves over the Western Arabian Gulf (WAG) which is a vital habitat and resource for the local ecosystem, according to the United Stated Geological Survey (USGS) mangrove database through spectral analysis. Change detection analysis is conducted on mangrove forests along the Saudi Arabian coast of the WAG for the years …