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Nutrition

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

2017

N-3

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Effect Of N-3 And N-6 Polyunsaturated Fatty Acids On Inflammation, Tao Xu May 2017

Effect Of N-3 And N-6 Polyunsaturated Fatty Acids On Inflammation, Tao Xu

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Intake of polyunsaturated fatty acids (PUFA) has changed drastically in the past century in the American diet has received attention due to potential effects on chronic inflammation-related metabolic diseases. In this project, the effects of dietary PUFA content and the n-6 to n-3 ratio on inflammatory responses in the acute and chronic inflammation models were evaluated. The PUFA content was modified on a Western diet background to deliver both n-6 and n-3 intakes at the 10th and 90th percentile of the population in the United States, and models of acute and chronic inflammation were tested in mice model. …